Microcystin poisoning in roe deer (Capreolus capreolus)

被引:23
|
作者
Handeland, Kjell [1 ]
Ostensvik, Oyvin [2 ]
机构
[1] Natl Vet Inst, Sect Wildlife Dis, Oslo, Norway
[2] Norwegian Sch Vet Sci, Dept Food Safety & Infect Biol, Oslo, Norway
关键词
Cyanobacteria; Blue-green algae; Hepatotoxicosis; Microcystin; Roe deer; Capreolus capreolus; Deer; Cervidae; Wildlife; NATIONAL-PARK; CYANOBACTERIA; AERUGINOSA; CYANOTOXINS; FLAMINGOS; MORTALITY; MICE; LR;
D O I
10.1016/j.toxicon.2010.06.023
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Acute cyanobacterial hepatotoxicosis in a wild roe deer (Capreolus capreolus) from Norway is reported. The diagnosis was based upon the demonstration of typical liver lesions and high liver concentrations of microcystins. The liver was markedly enlarged and histopathological examination revealed diffuse hepatocellular dissociation, degeneration and necrosis and perisinusoidal haemorrhage. Liquid chromatography-mass spectrometry demonstrated the presence of 1361 ng microcystin-YR, -LR and -RR per gram liver (wet weight). This is believed to be the first report of cyanobacterial intoxication in wild mammalian species as confirmed by demonstration of high toxin levels in the animal's tissues. (C) 2010 Elsevier Ltd. All rights reserved.
引用
收藏
页码:1076 / 1078
页数:3
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