Immune Checkpoint Inhibition in Prostate Cancer

被引:14
|
作者
Nicholson, Lowell Thorndike [1 ]
Fong, Lawrence [2 ]
机构
[1] Univ Calif San Francisco, Dept Med, San Francisco, CA 94143 USA
[2] Univ Calif San Francisco, Div Hematol & Oncol, San Francisco, CA 94143 USA
来源
TRENDS IN CANCER | 2020年 / 6卷 / 03期
关键词
DOUBLE-BLIND; IPILIMUMAB; PLACEBO; SAFETY; TUMORS;
D O I
10.1016/j.trecan.2020.01.003
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Although immunotherapy has proved to be effective in a variety of cancer subtypes, the role of immune checkpoint inhibition in the treatment of prostate cancer remains unclear. Here we review results from the latest clinical trials and discuss data suggesting that certain genetic mutations may confer increased sensitivity to immune checkpoint blockade.
引用
收藏
页码:174 / 177
页数:5
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