Newer Biologic and Small-Molecule Therapies for Inflammatory Bowel Disease

被引:170
|
作者
Baumgart, Daniel C. [1 ]
Le Berre, Catherine [2 ,3 ]
机构
[1] Univ Alberta, Div Gastroenterol, 130 Univ Campus NW, Edmonton, AB T6G 2X8, Canada
[2] Nantes Univ Hosp, Inst Malad Appareil Digestif, Nantes, France
[3] Univ Lorraine, Nancy Univ Hosp, Dept Gastroenterol, Vandoeuvre Les Nancy, France
来源
NEW ENGLAND JOURNAL OF MEDICINE | 2021年 / 385卷 / 14期
关键词
FECAL MICROBIOTA TRANSPLANTATION; SEVERE CROHNS-DISEASE; ACTIVE ULCERATIVE-COLITIS; ANTI-TNF DISCONTINUATION; MAINTENANCE THERAPY; DOUBLE-BLIND; INDUCTION THERAPY; COMBINATION THERAPY; OZANIMOD INDUCTION; RANDOMIZED-TRIAL;
D O I
10.1056/NEJMra1907607
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Newer Biologic and Small-Molecule Therapies for IBD There is still no cure for inflammatory bowel disease. This review covers newer treatments that reflect our understanding of the complex pathogenesis of IBD, with a focus on clinical and endoscopic remission and more precise molecular targeting of inflammatory cascades.
引用
收藏
页码:1302 / 1315
页数:14
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