Poly(ethylene glycol)-poly(lactic acid) copolymers for drug carriers

被引：0
|
作者：
Li, Xiaoran [1 ]
Yuan, Xiaoyan [1 ]
机构：
[1] Tianjin Univ, Sch Mat Sci & Engn, Tianjin 300072, Peoples R China
来源：
PROGRESS IN CHEMISTRY | 2007年 / 19卷 / 06期
关键词：
poly ( ethylene glycol)-poly ( lactic acid) copolymers; drug carriers; controlled release; electrospinning;
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Recent progress in hydrophilic modification of poly( lactic acid) copolymerized with poly( ethylene glycol) is reviewed in this paper. Synthesis methods of poly(ethylene glycol) -poly (lactic acid) copolymers (PEG-PLA) with block or star structures and their terminated derivatives, including their applications in loading hydrophilic, hydrophobic or protein drugs in forms of micelle, microparticle, hydrogel and vesicle are summaried. Especially, drug release behaviors of ultrafine PEG-PLA fibers prepared by electrospinning for drug carriers are introduced.
引用
收藏
页码：973 / 981
页数：9
相关论文
共 69 条
  • [1] Self-porating polymersomes of PEG-PLA and PEG-PCL: hydrolysis-triggered controlled release vesicles
    Ahmed, F
    Discher, DE
    [J]. JOURNAL OF CONTROLLED RELEASE, 2004, 96 (01) : 37 - 53
  • [2] Polymersomes as viral capsid mimics
    Ahmed, Fariyal
    Photos, Peter J.
    Discher, Dennis E.
    [J]. DRUG DEVELOPMENT RESEARCH, 2006, 67 (01) : 4 - 14
  • [3] Biodegradable amphiphilic multiblock copolymers and their implications for biomedical applications
    Bae, YH
    Huh, KM
    Kim, Y
    Park, KH
    [J]. JOURNAL OF CONTROLLED RELEASE, 2000, 64 (1-3) : 3 - 13
  • [4] Novel amphiphilic triblock copolymer based on PPDO, PCL, and PEG: Synthesis, characterization, and aqueous dispersion
    Bahadur, K. C. Remant
    Bhattarai, Shanta Raj
    Aryal, Santosh
    Khil, Myung Seob
    Dharmaraj, N.
    Kim, Hak Yong
    [J]. COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, 2007, 292 (01) : 69 - 78
  • [5] Encapsulating Chondrocytes in degrading PEG hydrogels with high modulus: Engineering gel structural changes to facilitate cartilaginous tissue production
    Bryant, SJ
    Bender, RJ
    Durand, KL
    Anseth, KS
    [J]. BIOTECHNOLOGY AND BIOENGINEERING, 2004, 86 (07) : 747 - 755
  • [6] Synthesis, characterization, effect of architecture on crystallization, and spherulitic growth of poly(L-lactide)-b-poly(ethylene oxide) copolymers with different branch arms
    Cai, C
    Wang, L
    Dong, CM
    [J]. JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY, 2006, 44 (06) : 2034 - 2044
  • [7] CARMEN S, 1995, MACROMOLECULES, V28, P7295
  • [8] Synthesis and properties of poly(L-lactide)-poly (ethylene glycol) multiblock copolymers by coupling triblock copolymers
    Chen, WN
    Luo, WJ
    Wang, SG
    Bei, JZ
    [J]. POLYMERS FOR ADVANCED TECHNOLOGIES, 2003, 14 (3-5) : 245 - 253
  • [9] Sustained release of proteins from electrospun biodegradable fibers
    Chew, SY
    Wen, J
    Yim, EKF
    Leong, KW
    [J]. BIOMACROMOLECULES, 2005, 6 (04) : 2017 - 2024
  • [10] Star-shaped poly(ether-ester) block copolymers: Synthesis, characterization, and their physical properties
    Choi, YR
    Bae, YH
    Kim, SW
    [J]. MACROMOLECULES, 1998, 31 (25) : 8766 - 8774
1234567