Fabrication and Characterization of 3D Micro- and Nanoelectrodes for Neuron Recordings

被引：20

作者：

Dimaki, Maria ^{[1
]}

Vazquez, Patricia ^{[1
]}

Olsen, Mark Holm ^{[1
]}

Sasso, Luigi ^{[1
]}

Rodriguez-Trujillo, Romen ^{[1
]}

Vedarethinam, Indumathi ^{[1
]}

Svendsen, Winnie E. ^{[1
]}

机构：

[1] Tech Univ Denmark, Dept Micro & Nanotechnol, DTU Nanotech, Lyngby, Denmark

来源：

SENSORS | 2010年 / 10卷 / 11期

关键词：

3D electrodes; fabrication; neuron differentiation on chip; PT-TIP MICROELECTRODES; MULTIELECTRODE ARRAYS; BRAIN-SLICES; CELLS; SYSTEM; STIMULATION; ELECTRODES; EVOLUTION; IMPEDANCE; CULTURES;

D O I：

10.3390/s101110339

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

In this paper we discuss the fabrication and characterization of three dimensional (3D) micro- and nanoelectrodes with the goal of using them for extra- and intracellular studies. Two different types of electrodes will be described: high aspect ratio microelectrodes for studying the communication between cells and ultimately for brain slice recordings and small nanoelectrodes for highly localized measurements and ultimately for intracellular studies. Electrical and electrochemical characterization of these electrodes as well as the results of PC12 cell differentiation on chip will be presented and discussed.

引用

页码：10339 / 10355

页数：17

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