Tissue engineering of vascular bypass grafts: Role of endothelial cell extraction

被引:88
|
作者
Tiwari, A [1 ]
Salacinski, HJ [1 ]
Hamilton, G [1 ]
Seifalian, AM [1 ]
机构
[1] UCL, Royal Free Hosp, Royal Free & Univ Coll Med Sch, Dept Surg,Vascular Haemodynam Unit, London NW3 2QG, England
关键词
endothelium; extraction; biomaterials; seeding; tissue engineering; vascular prostheses;
D O I
10.1053/ejvs.2001.1316
中图分类号
R61 [外科手术学];
学科分类号
摘要
Surgical treatment of vascular disease has become common. The use of synthetic materials is limited to grafts larger than 5-6 mm, because of the frequency of occlusion observed with small-diameter prosthetics. An alternative would be a hybrid or tissue-engineered graft with the surface coated with a monolayer of the patients' own endothelial cells. This review examines the various techniques and technologies used to date in order to extract endothelial cells for such graft engineering.
引用
收藏
页码:193 / 201
页数:9
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