Eosinophilic Granulomatosis with Polyangiitis Relapse after COVID-19 Vaccination: A Case Report

被引：15
|
作者：
Costanzo, Giulia [1 ]
Ledda, Andrea Giovanni [1 ]
Ghisu, Alessandra [1 ]
Vacca, Matteo [1 ]
Firinu, Davide [1 ]
Del Giacco, Stefano [1 ]
机构：
[1] Univ Cagliari, Dept Med Sci & Publ Hlth, I-09131 Cagliari, Italy
来源：
VACCINES | 2022年 / 10卷 / 01期
关键词：
EGPA; COVID-19; vaccine; mRNA BNT162b2 vaccine; relapse;
D O I：
10.3390/vaccines10010013
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Background: We here describe the case of a 71-year-old Caucasian woman previously diagnosed with Eosinophilic Granulomatosis with Polyangiitis (EGPA) that had been treated with Mepolizumab, an anti-IL5 monoclonal antibody, since 2019 with a good clinical response. Methods: She had a mild COVID-19 in December 2020 and she tested negative for SARS-CoV-2 infection in only late January 2021. In April 2021 she received the first dose of mRNA BNT162b2 vaccine. Ten days later she developed myalgia, dyspnea and numbness of the limbs due to a relapse of EGPA that occurred during Mepolizumab treatment.
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页数：5
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