Design of combinatorial libraries for the rapid lead optimization of glucagon antagonists.

被引：0
|
作者：
Shi, SH
Kuki, A
Ling, AL
Ling, A
Plewe, M
Gonzalez, J
机构：
[1] Agouron Pharmaceut, Dept Computat, Alanex Div, San Diego, CA 92121 USA
[2] Agouron Pharmaceut, Med Chem, Alanex Div, San Diego, CA USA
[3] Agouron Pharmaceut, Combinatorial Chem Technol, Alanex Div, San Diego, CA USA
来源：
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY | 2000年 / 220卷
关键词：
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
17-CINF
引用
收藏
页码：U197 / U197
页数：1
相关论文
共 50 条
  • [1] Screening combinatorial libraries for LEF-1 antagonists.
    Cohen, SB
    Fink, B
    Boger, DL
    Vogt, PK
    [J]. CLINICAL CANCER RESEARCH, 2000, 6 : 4476S - 4476S
  • [2] Design and synthesis of quinolines as glucagon antagonists.
    Cook, JH
    Doherty, EM
    Ladouceur, G
    Livingston, JN
    MacDougall, ML
    [J]. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1998, 216 : U287 - U287
  • [3] Discovery and optimization of potent nonpeptidic glucagon antagonists.
    Ladouceur, G
    Cook, J
    Doherty, E
    Jones, H
    Hertzog, D
    Hundertmark, T
    Korpusik, M
    Lease, T
    Livingston, J
    MacDougall, M
    Osterhout, M
    Phelan, K
    Romero, R
    Shao, C
    Schoen, W
    [J]. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1999, 218 : U973 - U973
  • [4] Rapid lead optimization through focused combinatorial libraries.
    Liu, RY
    Ho, KK
    Kultgen, SG
    Dong, GZ
    Geng, P
    Saionz, KW
    Guo, T
    [J]. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2003, 226 : U36 - U36
  • [5] Design and synthesis of pyridyl pyrroles as glucagon receptor antagonists.
    Kim, DS
    Leung, KP
    MacCoss, M
    Koch, GE
    Cascieri, MA
    Mantlo, NB
    Hagmann, WK
    [J]. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1999, 217 : U1175 - U1175
  • [6] Discovery of novel human glucagon receptor antagonists.
    Shen, DM
    Zhang, F
    Brady, EJ
    Candelore, MR
    Ding, VDH
    Jiang, G
    Mock, S
    Qureshi, SA
    Saperstein, R
    Tamvakopoulos, C
    Tong, X
    Tota, LM
    Wright, M
    Zheng, S
    Chapman, KT
    Zhang, BB
    Tata, JR
    Parmee, E
    [J]. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2005, 229 : U121 - U121
  • [7] Combinatorial synthesis of CCR5 antagonists.
    Willoughby, CA
    Berk, SC
    Rosauer, K
    Degrado, S
    Chapman, K
    Springer, MS
    DeMartino, JA
    Gould, SL
    Siciliano, SC
    Malkowitz, L
    Schleif, WA
    Hazuda, D
    Miller, M
    Kessler, R
    Danzisen, R
    Holmes, K
    Lineberger, J
    Carella, A
    Carver, G
    Emini, E
    [J]. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2001, 221 : U138 - U138
  • [8] Design, synthesis, and evaluation of integrin antagonists.
    Perkins, JJ
    Meissner, RS
    Duggan, ME
    Huff, JR
    Gould, RJ
    Lynch, RJ
    Leu, CT
    Nagy, RM
    Rodan, SB
    Wesolowski, GA
    Rodan, GA
    Hartman, GD
    [J]. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2001, 222 : U111 - +
  • [9] The design of combinatorial libraries
    Kubinyi, H
    [J]. DRUG DISCOVERY TODAY, 2002, 7 (09) : 503 - 504
  • [10] Second generation directed libraries for identification of growth factor antagonists.
    Zhang, J
    Rivers, G
    Burch, P
    Grundstrom, G
    Rusche, J
    Herlihy, W
    Jacobson, AR
    [J]. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1998, 215 : U908 - U908
12345