Tourism e-commerce is the integrated combination of electronic and tourism commerce, providing through internet tour products and service which meet the market demand. In this strategy the internet is the approach, and the tourism commerce activity is the core. However, as far as the present status of the Yangtze cruising products is concerned, there are some serious problems in the process of developing the on-line marketing for tourism, this has not only hindered the implementation of the tourism e-commerce on the Yangtze cruising products, but also restrained the development of the Yangtze cruise industry. This paper takes the tourism website owned by the biggest cruise ship corporation (CCOTC) on the Yangtze River as an example, and has studied the advantage and approach for the Yangtze cruise industry to develop the tourism e-commerce and proposed some relevant strategies.