Signal-mediated export of proteins from the malaria parasite to the host erythrocyte

被引：99
|
作者：
Marti, M
Baum, J
Rug, M
Tilley, L
Cowman, AF [1 ]
机构：
[1] Walter & Eliza Hall Inst Med Res, Melbourne, Vic 3050, Australia
[2] La Trobe Univ, Dept Biochem, Melbourne, Vic 3000, Australia
来源：
JOURNAL OF CELL BIOLOGY | 2005年 / 171卷 / 04期
关键词：
D O I：
10.1083/jcb.200508051
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
Intracellular parasites from the genus Plasmodium reside and multiply in a variety of cells during their development. After invasion of human erythrocytes, asexual stages from the most virulent malaria parasite, P. falciparum, drastically change their host cell and export remodelling and virulence proteins. Recent data demonstrate that a specific NH2-terminal signal conserved across the genus Plasmodium plays a central role in this export process.
引用
收藏
页码：587 / 592
页数：6
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