Electrochemical Detection of Norepinephrine in the Presence of Epinephrine, Uric Acid and Ascorbic Acid Using a Graphene-modified Electrode

被引：0
|
作者：
Ma, Xinying [1 ]
Chen, Meifeng [1 ]
Li, Xia [1 ]
Purushothaman, Anurag [2 ]
Li, Fuchuan [3 ]
机构：
[1] Heze Univ, Dept Chem & Chem Engn, Heze 274015, Peoples R China
[2] Univ Alabama Birmingham, Dept Pathol, Birmingham, AL 35294 USA
[3] Shandong Univ, Natl Glycoengn Res Ctr, Jinan 250012, Peoples R China
来源：
INTERNATIONAL JOURNAL OF ELECTROCHEMICAL SCIENCE | 2012年 / 7卷 / 02期
关键词：
Modified Electrode; Graphene; Norepinephrine; Reduction peak current; CATECHOLAMINES; DOPAMINE;
D O I：
暂无
中图分类号：
O646 [电化学、电解、磁化学];
学科分类号：
081704 ;
摘要：
A glassy carbon electrode was modified with graphene. In phosphate buffer solution, the modified electrode showed an excellent electrocatalytical effect on the oxidation of norepinephrine (NE). This was further used to determine NE in the presence of epinephrine, uric acid and ascorbic acid by cyclic voltammetry. The reduction peak current showed a linear relationship with the concentrations of NE in the range of 6.00x10(-7) to 1.20x10(-4) mol.L-1, with the detection limit of 4.00x10(-7) mol.L-1. The modified electrode can be used to selectively determine NE in the presence of epinephrine, uric acid and ascorbic acid by measuring reduction peak current in PBS pH 7.0. The method has high sensitivity, selectivity, stability, and has been successfully applied to analyzing injection samples of NE.
引用
收藏
页码：991 / 1000
页数：10
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