How does ageing affect the impact of medically unexplained symptoms and medically explained symptoms on health-related quality of life?

被引:22
|
作者
Hilderink, Peter H. [1 ]
Collard, Rose [2 ]
Rosmalen, Judith G. M. [3 ]
Voshaar, Richard C. Oude [3 ]
机构
[1] Practice Old Age Psychiat, Gendt, Netherlands
[2] Radboud Univ Nijmegen, Med Ctr, Dept Psychiat, Nijmegen Ctr Evidence Based Practice, NL-6525 ED Nijmegen, Netherlands
[3] Univ Groningen, Univ Med Ctr Groningen, Groningen, Netherlands
关键词
medically unexplained symptoms; quality of life; aged; medically explained; symptoms; CHRONIC PAIN; SOMATOFORM DISORDERS; OLDER-PEOPLE; AGE; SOMATIZATION; COMPLAINTS; YOUNGER; POPULATION; PSYCHIATRY; DEPRESSION;
D O I
10.1002/gps.4219
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
BackgroundPhysical symptoms significantly impair health-related quality of life (HRQoL), but age effects and differential effects of medically unexplained symptoms (MUS) and medically explained symptoms (MES) have hardly been examined. Our objective was to determine the effect of age on the impact of MUS and MES on HRQoL. MethodsIn a population-based cohort (n=946, aged 28-75years), MUS and MES were measured using the Composite International Diagnostic Interview and HRQoL using the EuroQol-5 dimensions (EQ-5D). Using multiple linear regression, we regressed MUS, MES and their interaction with age on HRQoL, adjusted for socio-demographic variables and the presence of depressive and anxiety disorders. In case of significant interaction terms, age-stratified results will be presented. ResultsIn the whole study population, the association between MUS and HRQoL was stronger (=-0.35; p<0.001) than between MES and HRQoL (=-0.26; p<0.001). Adjusted for depressive and anxiety disorders, differences between these associations decline (MUS: =-0.28, p<0.001; MES: =-0.25, p<0.001). Age significantly interacted with number of MUS in explaining variance in HRQoL but not with the number of MES. The impact of MUS on HRQoL is much larger in people aged below 65years (=-0.39, p<0.001) versus those aged 65years and over (=-0.21, p=0.002). In the older group, the association between MUS and HRQoL lost significance when adjusted for depressive and anxiety disorders (=-0.12 p=0.062). ConclusionOur results show that age affects the association between MUS and HRQoL, which suggest that older persons cope better with MUS than younger persons. Copyright (c) 2014 John Wiley & Sons, Ltd.
引用
收藏
页码:737 / 743
页数:7
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