Increase of cytochrome b mRNA by bis(2-hydroxyethyl) trisulfide in J774A.1 cells

被引:0
|
作者
Kohama, Y
Iida, K
Itoh, S
Tsujikawa, K
Mimura, T
机构
关键词
bis(2-hydroxyethyl) trisulfide; differential display; mitochondrial gene; cytochrome b; macrophage; Bacillus stearothermophilus;
D O I
暂无
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
The effect of a cytotoxic substance (bis(2-hydroxyethyl) trisulfide; BS-1), isolated from Bacillus stearothermophilus UK563, on messenger ribonucleic acid (mRNA) level in mouse macrophage-like J774A.1 cells was investigated by the method of differential display. The treatment of J774A.1 cells with BS-1 led us to detect the inducible gene. The sequence analysis revealed that the gene was identical to mouse mitochondrial cytochrome b. In fact, Northern blot analysis showed that cytochrome b mRNA in J774A.1 cells was increased by BS-1.
引用
收藏
页码:876 / 878
页数:3
相关论文
共 50 条
  • [1] MRNA but not plasmid DNA is efficiently transfected in murine J774A.1 macrophages
    Van de Parre, TJL
    Martinet, W
    Schrijvers, DM
    Herman, AG
    De Meyer, GRY
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2005, 327 (01) : 356 - 360
  • [2] In vitro uptake of amphiphilic, hydrogel nanoparticles by J774A.1 cells
    Missirlis, Dimitris
    Hubbell, Jeffrey A.
    JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, 2010, 93A (04) : 1557 - 1565
  • [3] Coxiella burnetii infection increases transferrin receptors on J774A.1 cells
    Howe, D
    Mallavia, LP
    INFECTION AND IMMUNITY, 1999, 67 (07) : 3236 - 3241
  • [4] The Immune Privileged Retina Mediates an Alternative Activation of J774A.1 Cells
    Lau, Chun H.
    Taylor, Andrew W.
    OCULAR IMMUNOLOGY AND INFLAMMATION, 2009, 17 (06) : 380 - 389
  • [5] 1,1-BIS(2-HYDROXYETHYL)HYDRAZONES
    WILEY, RH
    WHITE, HK
    IRICK, G
    JOURNAL OF ORGANIC CHEMISTRY, 1961, 26 (02): : 589 - &
  • [6] Effect of fumonisin B1 on inducible nitric oxide synthase and cyclooxygenase-2 in LPS-stimulated J774A.1 cells
    Meli, R
    Ferrante, MC
    Raso, GM
    Cavaliere, M
    Di Carlo, R
    Lucisano, A
    LIFE SCIENCES, 2000, 67 (23) : 2845 - 2853
  • [7] STUDIES ON THERMOPHILE PRODUCTS .6. ACTIVATION OF MOUSE PERITONEAL-MACROPHAGES BY BIS(2-HYDROXYETHYL) TRISULFIDE
    KOHAMA, Y
    IIDA, K
    TANAKA, K
    SEMBA, T
    ITOH, M
    TERAMOTO, T
    TSUJIKAWA, K
    MIMURA, T
    BIOLOGICAL & PHARMACEUTICAL BULLETIN, 1993, 16 (10) : 973 - 977
  • [8] 1,2-BIS(2-HYDROXYETHYL)HYDRAZINE AND DERIVATIVES
    NIELSEN, AT
    LAWRENCE, GW
    JOURNAL OF ORGANIC CHEMISTRY, 1977, 42 (17): : 2900 - 2902
  • [9] The effect of lead on nitric oxide production in stimulated (J774A.1) macrophage cells.
    Ikajddi, A
    Soliman, KFA
    FASEB JOURNAL, 1998, 12 (04): : A463 - A463
  • [10] MECHANISM OF REDUCTION OF BIS(2-HYDROXYETHYL) TRISULFIDE BY EAQ- AND .CO2- - SPECTRUM AND SCAVENGING OF RSS. RADICALS
    WU, Z
    BACK, TG
    AHMAD, R
    YAMDAGNI, R
    ARMSTRONG, DA
    JOURNAL OF PHYSICAL CHEMISTRY, 1982, 86 (22): : 4417 - 4422