High Affinity Bent β2 Integrin Binds Ligand in Cis and Regulates Inflammation

被引:0
|
作者
Fan, Zhichao [1 ]
McArdle, Sara [1 ]
Mikulski, Zbigniew [1 ]
Gutierrez, Edgar [2 ]
Ginsberg, Mark [3 ]
Groisman, Alex [2 ]
Ley, Klaus [1 ]
机构
[1] La Jolla Inst Allergy & Immunol, Div Inflammat Biol, La Jolla, CA USA
[2] Univ Calif San Diego, Dept Phys, La Jolla, CA 92093 USA
[3] Univ Calif San Diego, Dept Med, La Jolla, CA 92093 USA
来源
FASEB JOURNAL | 2016年 / 30卷
关键词
D O I
暂无
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
1210.2
引用
收藏
页数:1
相关论文
共 50 条
  • [1] Neutrophil recruitment limited by high affinity bent β2 integrin binding ligand in cis
    Fan, Zhichao
    McArdle, Sara
    Mikulski, Zbigniew
    Gutierrez, Edgar
    Ginsberg, Mark
    Groisman, Alex
    Ley, Klaus
    JOURNAL OF IMMUNOLOGY, 2016, 196
  • [2] Neutrophil recruitment limited by high-affinity bent β2 integrin binding ligand in cis
    Fan, Zhichao
    McArdle, Sara
    Marki, Alex
    Mikulski, Zbigniew
    Gutierrez, Edgar
    Engelhardt, Britta
    Deutsch, Urban
    Ginsberg, Mark
    Groisman, Alex
    Ley, Klaus
    NATURE COMMUNICATIONS, 2016, 7
  • [3] Neutrophil recruitment limited by high-affinity bent β2 integrin binding ligand in cis
    Zhichao Fan
    Sara McArdle
    Alex Marki
    Zbigniew Mikulski
    Edgar Gutierrez
    Britta Engelhardt
    Urban Deutsch
    Mark Ginsberg
    Alex Groisman
    Klaus Ley
    Nature Communications, 7
  • [4] High-Affinity Bent β2-Integrin Molecules in Arresting Neutrophils Face Each Other through Binding to ICAMs In cis
    Fan, Zhichao
    Kiosses, William Bill
    Sun, Hao
    Orecchioni, Marco
    Ghosheh, Yanal
    Zajonc, Dirk M.
    Arnaout, M. Amin
    Gutierrez, Edgar
    Groisman, Alex
    Ginsberg, Mark H.
    Ley, Klaus
    CELL REPORTS, 2019, 26 (01): : 119 - +
  • [5] High affinity-bent β2 integrin molecules in arresting neutrophils face each other: role of binding to ICAMs in cis (a study of super-resolution microscopy).
    Fan, Z.
    Kiosses, W. B.
    Ghosheh, Y.
    Zajonc, D. M.
    Arnaout, M.
    Gutierrez, E.
    Groisman, A.
    Ley, K.
    MOLECULAR BIOLOGY OF THE CELL, 2018, 29 (26)
  • [6] Cation-π interaction regulates ligand-binding affinity and signaling of integrin α4β7
    Pan, YouDong
    Zhang, Kun
    Qi, JunPeng
    Yue, Jiao
    Springer, Timothy A.
    Chen, JianFeng
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2010, 107 (50) : 21388 - 21393
  • [7] Kindlin-2 directly binds actin and regulates integrin outside-in signaling
    Bledzka, Kamila
    Bialkowska, Katarzyna
    Sossey-Alaoui, Khalid
    Vaynberg, Julia
    Pluskota, Elzbieta
    Qin, Jun
    Plow, Edward E.
    JOURNAL OF CELL BIOLOGY, 2016, 213 (01): : 97 - 108
  • [8] WAVE2 regulates high-affinity integrin binding by recruiting vinculin and talin to the immunological synapse
    Nolz, Jeffrey C.
    Medeiros, Ricardo B.
    Mitchell, Jason S.
    Zhu, Peimin
    Freedman, Bruce D.
    Shimizu, Yoji
    Billadeau, Daniel D.
    MOLECULAR AND CELLULAR BIOLOGY, 2007, 27 (17) : 5986 - 6000
  • [9] Extracellular protein disulfide isomerase regulates ligand-binding activity of αMβ2 integrin and neutrophil recruitment during vascular inflammation
    Hahm, Eunsil
    Li, Jing
    Kim, Kyungho
    Huh, Sungjin
    Rogelj, Snezna
    Cho, Jaehyung
    BLOOD, 2013, 121 (19) : 3789 - 3800
  • [10] Phosphatidylserine Reversibly Binds Cu2+ with Extremely High Affinity
    Monson, Christopher F.
    Cong, Xiao
    Robison, Aaron D.
    Pace, Hudson P.
    Liu, Chunming
    Poyton, Matthew F.
    Cremer, Paul S.
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2012, 134 (18) : 7773 - 7779