Oral Immunotherapy for Food Allergy: A Spanish Guideline. Egg and Milk Immunotherapy Spanish Guide (ITEMS GUIDE). Part II: Maintenance Phase of Cow Milk (CM) and Egg Oral Immunotherapy (OIT), Special Treatment Dosing Schedules. Models of Dosing Schedules of OIT With CM and Egg

被引：15

作者：

Martorell, A. ^{[1
]}

Alonso, E. ^{[2
]}

Echeverria, L. ^{[3
]}

Escudero, C. ^{[4
]}

Garcia-Rodriguez, R. ^{[5
]}

Blasco, C. ^{[6
]}

Bone, J. ^{[7
]}

Borja-Segade, J. ^{[5
]}

Bracamonte, T. ^{[3
]}

Claver, A. ^{[8
]}

Corzo, J. L. ^{[9
]}

De la Hoz, B. ^{[10
]}

Del Olmo, R. ^{[11
]}

Dominguez, O. ^{[12
]}

Fuentes-Aparicio, V ^{[13
]}

Guallar, I ^{[7
]}

Larramona, H. ^{[14
]}

Martin-Munoz, F. ^{[15
]}

Matheu, V ^{[16
]}

Michavila, A. ^{[17
]}

Ojeda, I ^{[18
]}

Ojeda, P. ^{[18
]}

Piquer, M. ^{[12
]}

Poza, P. ^{[16
]}

Reche, M. ^{[19
]}

del Rio P, Rodriguez ^{[4
]}

Rodriguez, M. ^{[20
]}

Ruano, F. ^{[21
]}

Sanchez-Garcia, S. ^{[4
]}

Terrados, S. ^{[22
]}

Valdesoiro, L. ^{[14
]}

Vazquez-Ortiz, M. ^{[23
]}

机构：

[1] Univ Gen Hosp, Dept Allergol, Valencia, Valencia, Spain

[2] Gregorio Maranon Hosp, Dept Pediat Allergy, Madrid, Spain

[3] Severo Ochoa Univ Hosp, Dept Pediat Allergy, Leganes, Spain

[4] Nino Jesus Univ Childrens Hosp, Dept Pediat Allergy, Madrid, Spain

[5] Univ Gen Hosp, Dept Allergol, Ciudad Real, Spain

[6] Vall dHebron Hosp, Dept Pediat Allergy, Barcelona, Spain

[7] Miguel Servet Univ Hosp, Dept Pediat Allergy, Zaragoza, Spain

[8] Quiron Dexeus Univ Hosp, Barcelona, Spain

[9] Carlos Haya Univ Hosp, Dept Pediat Allergy, Malaga, Spain

[10] Ramon & Cajal Hosp, Dept Allergol, Madrid, Spain

[11] Univ Hosp, Dept Pediat Allergy, Mostoles, Spain

[12] San Joan de Deu Hosp, Dept Pediat Allergy, Barcelona, Spain

[13] San Carlos Clin Hosp, Dept Allergol, Madrid, Spain

[14] Parc Tauli Univ Hosp, Dept Pediat Allergy, Sabadell, Spain

[15] La Paz Pediat Hosp, Dept Allergol, Madrid, Spain

[16] Allergol Unit North Chest Hosp, Santa Cruz De Tenerife, Spain

[17] Gen Hosp, Dept Pediat Allergy, Castellon de La Plana, Spain

[18] Ojeda Clin, Madrid, Spain

[19] Infanta Sofia Hosp, Dept Allergol, San Sebastian De Reyes, Spain

[20] Alcorcon Fdn Hosp, Dept Allergol, Alcorcon, Spain

[21] Infanta Leonor Hosp, Dept Allergy, Madrid, Spain

[22] Ramon & Cajal Hosp, Dept Pediat Allergy, Madrid, Spain

[23] Imperial Coll London, Dept Med, Pediat Allergy, London, England

来源：

JOURNAL OF INVESTIGATIONAL ALLERGOLOGY AND CLINICAL IMMUNOLOGY | 2017年 / 27卷 / 05期

基金：

欧盟地平线“2020”;

关键词：

Guide; Oral immunotherapy; Desensitization; Specific oral tolerance induction; Milk allergy; Egg allergy; Omalizumab; Sublingual immunotherapy; TERM-FOLLOW-UP; IGE-ASSISTED DESENSITIZATION; RAW HENS EGG; TOLERANCE INDUCTION; DOUBLE-BLIND; SUBLINGUAL IMMUNOTHERAPY; PEANUT ALLERGY; SUSTAINED UNRESPONSIVENESS; PEDIATRIC-PATIENTS; MULTICENTER TRIAL;

D O I：

10.18176/jiaci.0178

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

Introduction: Cow milk and egg are the most frequent causes of food allergy in the first years of life. Oral immunotherapy (OIT) has been investigated as an alternative to avoidance diets. No clinical practice guidelines on the management of OIT with milk and egg are currently available. Objectives: To develop clinical guidelines for OIT based on available scientific evidence and the opinions of experts. Methods: A review was made of studies published between 1984 and June 2016, doctoral theses published in Spain, summaries of communications at scientific meetings (SEAIC, SEICAP, EAACI, and AAAAI), and the consensus of opinion established by a group of experts from the scientific societies SEICAP and SEAIC. Results: Recommendations were established regarding the indications, requirements and practical aspects of the different phases of Oft as well as special protocols for patients at high risk of adverse reactions. Conclusions: Clinical practice guidelines based on the consensus reached between Spanish experts are presented for the management of OIT with milk and egg.

引用

页码：279 / 290

页数：12

共 5 条

[1] Oral immunotherapy for food allergy: A Spanish guideline. Egg and milk immunotherapy Spanish guide (ITEMS GUIDE). Part 2: Maintenance phase of cow milk (CM) and egg oral immunotherapy (01T), special treatment dosing schedules. Models of dosing schedules of OIT with CM and EGG*
Martorell, A.
Alonso, E.
Echeverria, L.
Escudero, C.
Garcia-Rodriguez, R.
Blasco, C.
Bone, J.
Borja-Segade, J.
Bracamonte, T.
Claver, A.
Corzo, J. L.
De la Hoz, B.
Del Olmo, R.
Dominguez, O.
Fuentes-Aparicio, V.
Guallar, I.
Larramona, H.
Martin-Munoz, F.
Matheu, V.
Michavila, A.
Ojeda, I.
Ojeda, P.
Piquer, M.
Poza, P.
Reche, M.
Rodriguez del Rio, P.
Rodriguez, M.
Ruano, F.
Sanchez-Garcia, S.
Terrados, S.
Valdesoiro, L.
Vazquez-Ortiz, M.
[J]. ALLERGOLOGIA ET IMMUNOPATHOLOGIA, 2017, 45 (05) : 508 - 518
[2] Oral immunotherapy for food allergy: A Spanish guideline. Immunotherapy egg and milk Spanish guide (items guide). Part I: Cow milk and egg oral immunotherapy: Introduction, methodology, rationale, current state, indications contraindications and oral immunotherapy build-up phase
Martorell, A.
Alonso, E.
Echeverria, L.
Escudero, C.
Garcia-Rodriguez, R.
Blasco, C.
Bone, J.
Borja-Segade, J.
Bracamonte, T.
Claver, A.
Corzo, J. L.
De la Hoz, B.
Del Olmo, R.
Dominguez, O.
Fuentes-Aparicio, V.
Guallar, I.
Larramona, H.
Martin-Munoz, F.
Matheu, V.
Michavila, A.
Ojeda, I.
Ojeda, P.
Piquer, M.
Poza, P.
Reche, M.
Rodriguez del Rio, P.
Rodriguez, M.
Ruano, F.
Sanchez-Garcia, S.
Terrados, S.
Valdesoiro, L.
Vazquez-Ortiz, M.
[J]. ALLERGOLOGIA ET IMMUNOPATHOLOGIA, 2017, 45 (04) : 393 - 404
[3] Oral Immunotherapy for Food Allergy: A Spanish Guideline. Immunotherapy Egg and Milk Spanish Guide (ITEMS Guide). Part I: Cow Milk and Egg Oral. Immunotherapy: Introduction, Methodology, Rationale, Current State, Indications, Contraindications, and Oral Immunotherapy Build-up Phase
Martorell, A.
Alonso, E.
Echeverria, L.
Escudero, C.
Garcia-Rodriguez, R.
Blasco, C.
Bone, J.
Borja-Segade, J.
Bracamonte, T.
Claver, A.
Corzo, J. L.
De la Hoz, B.
Del Olmo, R.
Dominguez, O.
Fuentes-Aparicio, V
Guallar, I
Larramona, H.
Martin-Munoz, F.
Matheu, V
Michavila, A.
Ojeda, I
Ojeda, P.
Piquer, M.
Poza, P.
Reche, M.
Rodriguez del Rio, P.
Rodriguez, M.
Ruano, F.
Sanchez-Garcia, S.
Terrados, S.
Valdesoiro, L.
Vazquez-Ortiz, M.
[J]. JOURNAL OF INVESTIGATIONAL ALLERGOLOGY AND CLINICAL IMMUNOLOGY, 2017, 27 (04) : 225 - 237
[4] Life-threatening reactions to oral immunotherapy (OIT) in egg and cow's milk (CM) allergic teenagers
Vazquez-Ortiz, M.
Giner, M. T.
Piquer, M.
Dominguez, O.
Alvaro, M.
Lozano, J.
Jimenez-Feijoo, R. M.
Plaza, A. M.
[J]. ALLERGY, 2014, 69 : 278 - 278
[5] A Randomized, Double-Blind, Placebo-Controlled Trial of Omalizumab Combined with Oral Immunotherapy (OIT) in the Treatment of Cow's Milk Allergy (CMA): Safety of Dosing
Kim, Jennifer S.
Wood, Robert A.
Lindblad, Robert
Noone, Sally A.
Paterakis, Melissa N.
Henning, Alice
Nadeau, Kari C.
Spann, Kyrsten
Sampson, Hugh A.
[J]. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2014, 133 (02) : AB403 - AB403

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