Quantitation of absorbers in turbid media using time-integrated spectroscopy based on microscopic Beer-Lambert law

被引:13
|
作者
Zhang, HD [1 ]
Miwa, M [1 ]
Yamashita, Y [1 ]
Tsuchiya, Y [1 ]
机构
[1] Hamamatsu Photon KK, Cent Res Lab, Hamakita 434, Japan
关键词
absolute concentration of absorbers; mean path length; temporal integration of the impulse response; tissue spectroscopy;
D O I
10.1143/JJAP.37.2724
中图分类号
O59 [应用物理学];
学科分类号
摘要
Based on the microscopic Beer-Lambert law, two practical time-integrated spectroscopy (TIS) methods, called dual-wavelength spectroscopy method, and dual-wavelength and dual-site spectroscopy method, are described to determine the absolute concentration of an absorber in variously shaped turbid media. We demonstrate, for the first time, the validity of the TIS methods by means of experiments in which the absolute concentrations of an absorber in a tissue-like phantom were determined with errors less than several percent. The advantages and disadvantages of both methods are also discussed.
引用
收藏
页码:2724 / 2727
页数:4
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