Promoting Diversity in the Cytoskeleton through STEM-Structural Transitions and Energetics of Microtubule Subunits

被引：0

作者：

Ohi, Ryoma ^{[1
,2
]}

Verhey, Kristen J. ^{[1
]}

机构：

[1] Univ Michigan, Dept Cell & Dev Biol, Med Sch, Ann Arbor, MI 48109 USA

[2] Univ Michigan, Inst Life Sci, Ann Arbor, MI 48109 USA

来源：

DEVELOPMENTAL CELL | 2018年 / 47卷 / 02期

关键词：

HUMAN TUBULIN; PURIFICATION; DYNAMICS;

D O I：

10.1016/j.devcel.2018.10.008

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

All microtubules assemble from tubulin subunits, but the functional impact of tubulin isotypes has been unclear. Reporting in Developmental Cell, Chaaban et al. (2018) and Ti et al. (2018) show that tubulin isotypes differ in their conformational flexibility, which alters microtubule dynamics and architecture, yet maintain "lock-and-key'' interactions with neighbors.

引用

页码：137 / 139

页数：4

共 3 条

[1] Microtubule Plus End Dynamics - Do We Know How Microtubules Grow? Cells boost microtubule growth by promoting distinct structural transitions at growing microtubule ends
van Haren, Jeffrey
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[J]. BIOESSAYS, 2019, 41 (03)
[2] Promoting student diversity and success in STEM fields through the use of interdisciplinary learning communities
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[3] Promoting gender diversity in STEM faculty through leadership development From local and national leadership workshops to the online LEAD-it-Yourself! toolkit
Yen, Joyce
Riskin, Eve A.
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Spyridakis, Jan H.
Carrigan, Coleen M.
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[J]. EQUALITY DIVERSITY AND INCLUSION, 2019, 38 (03): : 382 - 398

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