An efficient two-photon fluorescent probe for monitoring mitochondrial singlet oxygen in tissues during photodynamic therapy

被引：76

作者：

Liu, Hong-Wen ^{[1
]}

Xu, Shuai ^{[1
]}

Wang, Peng ^{[1
]}

Hu, Xiao-Xiao ^{[1
]}

Zhang, Jing ^{[1
]}

Yuan, Lin ^{[1
]}

Zhang, Xiao-Bing ^{[1
]}

Tan, Weihong ^{[1
]}

机构：

[1] Hunan Univ, State Key Lab Chemo Biosensing & Chemometr, Coll Chem & Chem Engn, Mol Sci & Biomed Lab, Changsha 410082, Hunan, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2016年 / 52卷 / 83期

关键词：

APOPTOSIS; COMPLEX; DESIGN;

D O I：

10.1039/c6cc05880a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A promising two-photon fluorescent probe MNAH for detecting O-1(2) during the PDT process in mitochondria was proposed for the first time. MNAH was successfully applied for two-photon imaging of O-1(2) in living cells and tissues during the PDT process with deep-tissue imaging depth. MNAH can be a powerful molecular tool for studying O-1(2) generation in mitochondria during the PDT process.

引用

页码：12330 / 12333

页数：4

共 50 条

[1] Efficient Singlet Oxygen Generation in Metal Nanoclusters for Two-Photon Photodynamic Therapy Applications
Ho-Wu, Rosina
Yau, Sung Hei
Goodson, Theodore, III
[J]. JOURNAL OF PHYSICAL CHEMISTRY B, 2017, 121 (43): : 10073 - 10080
[2] Diketopyrrolopyrrole-Porphyrin Conjugates with High Two-Photon Absorption and Singlet Oxygen Generation for Two-Photon Photodynamic Therapy
Schmitt, Julie
Heitz, Valerie
Sour, Angelique
Bolze, Frederic
Ftouni, Hussein
Nicoud, Jean-Francois
Flamigni, Lucia
Ventura, Barbara
[J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2015, 54 (01) : 169 - 173
[3] Monitoring hydrogen polysulfide during ferroptosis with a two-photon fluorescent probe
Di, Xiaojiao
Ge, Chao
Liu, Yani
Shao, Chenwen
Zhu, Hai-Liang
Liu, Hong-Ke
Qian, Yong
[J]. TALANTA, 2021, 232 (232)
[4] A two-photon fluorescent probe for colorimetric and ratiometric monitoring of mercury in live cells and tissues
Chen, Liyan
Park, Sang Jun
Wu, Di
Kim, Hwan Myung
Yoon, Juyoung
[J]. CHEMICAL COMMUNICATIONS, 2019, 55 (12) : 1766 - 1769
[5] A fluorescent benzothiazole probe with efficient two-photon absorption
Echevarria, Lorenzo
Moreno, Ivan
Camacho, Jose
Carmen Salazar, Mary
Hernandez, Antonio
[J]. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 2012, 97 : 274 - 276
[6] A Two-Photon Fluorescent Probe for Thiols in Live Cells and Tissues
Lee, Jun Han
Lim, Chang Su
Tian, Yu Shun
Han, Ji Hee
Cho, Bong Rae
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2010, 132 (04) : 1216 - +
[7] A FRET Based Two-Photon Fluorescent Probe for Visualizing Mitochondrial Thiols of Living Cells and Tissues
Liu, Zhengkun
Wang, Qianqian
Wang, Hao
Su, Wenting
Dong, Shouliang
[J]. SENSORS, 2020, 20 (06)
[8] Monitoring Singlet Oxygen and Hydroxyl Radical Formation with Fluorescent Probes During Photodynamic Therapy
Price, Michael
Reiners, John J.
Santiago, Ann Marie
Kessel, David
[J]. PHOTOCHEMISTRY AND PHOTOBIOLOGY, 2009, 85 (05) : 1177 - 1181
[9] Far-Red Fluorescence Probe for Monitoring Singlet Oxygen during Photodynamic Therapy
Kim, Sooyeon
Tachikawa, Takashi
Fujitsuka, Mamoru
Majima, Tetsuro
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2014, 136 (33) : 11707 - 11715
[10] Ratiometric Detection of Mitochondrial Thiols with a Two-Photon Fluorescent Probe
Lim, Chang Su
Masanta, Goutam
Kim, Hyung Joong
Han, Ji Hee
Kim, Hwan Myung
Cho, Bong Rae
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2011, 133 (29) : 11132 - 11135

← 1 2 3 4 5 →