Ceftolozane/Tazobactam Treatment of Multidrug-resistant Pseudomonas aeruginosa Infections in Children

被引：7
|
作者：
Molloy, Leah [1 ,2 ]
Abdulhamid, Ibrahim [2 ,3 ,4 ]
Srivastava, Ruma [2 ,3 ,4 ]
Ang, Jocelyn Y. [2 ,4 ,5 ]
机构：
[1] Childrens Hosp Michigan, Dept Pharm, 3901 Beaubien Blvd, Detroit, MI 48201 USA
[2] Childrens Hosp Michigan, Detroit Med Ctr, Detroit, MI 48201 USA
[3] Wayne State Univ, Div Pulm Med, Detroit, MI USA
[4] Wayne State Univ, Div Infect Dis, Detroit, MI USA
[5] Wayne State Univ, Sch Med, Detroit, MI USA
来源：
PEDIATRIC INFECTIOUS DISEASE JOURNAL | 2020年 / 39卷 / 05期
关键词：
ceftolozane; tazobactam; multidrug-resistant; Pseudomonas aeruginosa;
D O I：
10.1097/INF.0000000000002593
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
The clinical use, safety and effectiveness of ceftolozane/tazobactam among 13 patients 3 months to 19 years of age infected with multidrug-resistant Pseudomonas aeruginosa are described. All but one patient achieved clinical cure after initial treatment. Adverse drug events attributed to treatment included transaminitis and neutropenia which occurred in 2 patients and resolved upon dose reduction.
引用
收藏
页码：419 / 420
页数：2
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