Corpus callosum disorders and associated malformations in paediatric epilepsy: MRI analytic study

To assess the effectiveness of MRI in identifying the spectrum of corpus callosum anomalies in epileptic paediatric patients, a descriptive case series was studied in the General Paediatric Hospital, Baghdad from March 2017 to March 2020.A total of 52 patients with ages ranging from 4 months to 14 years were included. The Imaging criteria included MRI evaluation showing spectrum of anomalies involving the corpus callosum with malformation of cortical development, lipoma, Dandy Walker syndrome and Chiari malformation. Demographic data was recorded. The study included 52 patients with ages ranging from 4 months to 14 years, (mean age 5.94 +/- 4.08 years). There were 31(59.7 %) males and 21(40.3%) females diagnosed as 34(65%) agenesis, 25(48%) partial agenesis, 9(17.3%) complete agenesis and 18(34.7%) hypoplasia of corpus callosum. Other malformations noted in 32 patients included, Chiari malformation, cortical neuromigration disorders, Dandy Walker malformation, lipoma, cerebellar hypoplasia, posterior fossa arachnoid cyst and Chiari 2 malformation. Imaging evaluation in epilepsies, effectively detects callosal disorders and associated malformations, which add valuable data improving clinical management, seizure control clinical management and further decision-making.