Intralesional Therapy for In-transit and Satellite Metastases in Melanoma

被引：5
|
作者：
Feeney, Kendra J. [1 ]
Mastrangelo, Michael J. [1 ]
机构：
[1] Thomas Jefferson Univ, Sidney Kimmel Sch Med, Dept Med Oncol, Philadelphia, PA 19107 USA
来源：
SURGICAL ONCOLOGY CLINICS OF NORTH AMERICA | 2015年 / 24卷 / 02期
关键词：
Intralesional therapy; Bacille Calmette-Guerin; Vaccinia; Scarification; Granulocyte-macrophage colony-stimulating factor; Rose bengal; Melanoma; In-transit disease; TOPICAL IMIQUIMOD; PHASE-II; INTERLEUKIN-2; IMMUNOTHERAPY; BCG; REGRESSION;
D O I：
10.1016/j.soc.2014.12.007
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Intratumoral therapy with bacteria/bacterial products dates to at least the 1890s. Over the decades this has expanded beyond the use of microbes and microbial products to include chemicals, cancer chemotherapeutic agents, cytokines, recombinant organisms, and hybrid molecules. The appeal of this method of delivery is the ability to deliver high concentrations of the therapeutic agent directly to the tumor, often with minimal side effects. This article summarizes the use and efficacy of the various agents used in the past and present in the treatment of in-transit and satellite metastases in melanoma.
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收藏
页码：299 / +
页数：11
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