Sero-epidemiology and risk factor analysis of human brucellosis in Punjab, Pakistan: a cross sectional study

被引:3
|
作者
Nawaz, Z. [1 ]
Shafique, M. [1 ]
Zahoor, M. A. [1 ]
Siddique, A. B. [1 ]
Ali, S. [2 ]
Arshad, R. [3 ]
Kausar, S. [1 ]
Khan, K. [4 ]
Asad, M. [1 ]
Rehman, A. U. [1 ]
Masih, I [1 ]
机构
[1] Govt Coll Univ Faisalabad, Dept Microbiol, Punjab, Pakistan
[2] Vet Res Inst, Lahore, Punjab, Pakistan
[3] Islamia Univ Bahawalpur, Univ Coll Convent Med, Punjab, Pakistan
[4] DHQ Hosp, Bhakkar, Punjab, Pakistan
关键词
Human brucellosis; risk factors; RBPT; ELISA; Pakistan; SEROPREVALENCE; DIAGNOSIS; ABORTUS;
D O I
10.47665/tb.38.3.084
中图分类号
R38 [医学寄生虫学]; Q [生物科学];
学科分类号
07 ; 0710 ; 09 ; 100103 ;
摘要
Human brucellosis is a neglected zoonotic problem worldwide with a high degree of morbidity in humans and is mostly overlooked due to other febrile conditions. The aim of this study was to evaluate the sero-prevalence and risk factors of human brucellosis among subjects living in Punjab, Pakistan. In this cross-sectional study, human blood samples were collected from seven districts of Punjab, Pakistan. Information regarding personal data, demographic data and potential risk factors was collected through a structured questionnaire. Detection of anti-Brucella antibodies was done through Rose Bengal Plate Test (RBPT) and Enzyme Linked Immunosorbent Assay (ELISA). Descriptive analysis, Chi square test and Odds ratio was applied using STATA software version 12. The sero-prevalence of human brucellosis was 13.13% with significantly higher percentage in males 17.23% and age group 25-40 years 16.50% (P=< 0.001). The demographic factors positively associated with human brucellosis were lack of education (P = 0.003; OR = 1.85) and farming as an occupation (P =<0.001; OR = 2.50) Similarly, among the risk factors studied, keeping animals at home (P =<0.001; OR = 2.03), slaughtering of animals (P =<0.001; OR = 15.87) and consuming raw milk (P =<0.001; OR = 5.42) were the factors strongly connected with human brucellosis. A massive awareness should be given to livestock farmers and individuals directly linked to animals regarding risk factors and transmission of brucellosis. Consumption of unpasteurized milk and its products should be condemned to curtail this neglected disease.
引用
收藏
页码:413 / 419
页数:7
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