Studies towards the total synthesis of ouabagenin

被引:17
|
作者
Chen, L [1 ]
Deslongchamps, P [1 ]
机构
[1] Univ Sherbrooke, Inst Pharmacol Sherbrooke, Dept Chim, Organ Synth Lab, Sherbrooke, PQ J1H 5N4, Canada
关键词
organic chemistry; synthesis; cycloaddition; polycyclization; Michael reaction; Diels-Alder reaction; steroids; oubain; ouabagenin; natural products;
D O I
10.1139/V05-042
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
An anionic cyclization strategy developed in our laboratory was used to produce a versatile and convergent synthesis of an advanced tetracyclic intermediate for the construction of ouabagenin and closely related analogs.
引用
收藏
页码:728 / 740
页数:13
相关论文
共 50 条
  • [1] Studies towards the total synthesis of ouabagenin (vol 83, pg 728, 2005)
    Chen, L
    Deslongchamps, P
    CANADIAN JOURNAL OF CHEMISTRY, 2005, 83 (12) : 2144 - 2144
  • [2] Total synthesis of ouabagenin and ouabain
    Zhang, Hongxing
    Reddy, Maddi Sridhar
    Phoenix, Serge
    Deslongchamps, Pierre
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2008, 47 (07) : 1272 - 1275
  • [3] A convergent total synthesis of ouabagenin
    Mukai, Ken
    Kasuya, Satoshi
    Nakagawa, Yuki
    Urabe, Daisuke
    Inoue, Masayuki
    CHEMICAL SCIENCE, 2015, 6 (06) : 3383 - 3387
  • [4] Total Synthesis of Ouabagenin and Ouabain
    Reddy, Maddi Sridhar
    Zhang, Hongxing
    Phoenix, Serge
    Deslongchamps, Pierre
    CHEMISTRY-AN ASIAN JOURNAL, 2009, 4 (05) : 725 - 741
  • [5] Studies towards the total synthesis of anguidine
    Yingzhao, David
    Manetsch, Roman
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2019, 258
  • [6] Studies towards the total synthesis of Hygrocins
    Rasapalli, Sivappa
    Yarrapothu, Gangadhara Rao
    Jarugumilli, Goapalakrishna
    Yu, Menglong
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2012, 244
  • [7] STUDIES TOWARDS THE TOTAL SYNTHESIS OF LANKANOLIDE
    RAIMUNDO, BC
    HEATHCOCK, CH
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1995, 210 : 47 - ORGN
  • [8] Studies towards the total synthesis of (-)-dictyostatin
    Pohlki, Frauke
    Panek, James S.
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2006, 231
  • [9] Studies towards the total synthesis of Phostriecin
    Kumar, Gavireddy Chaithanya
    Muralikrishna, Katta
    Satyanarayana, Vavilapalli
    Kumar, Chintakrinda Suresh
    Yadav, Jhillu Singh
    TETRAHEDRON LETTERS, 2018, 59 (05) : 454 - 456
  • [10] Studies towards the total synthesis of contignasterol
    Izzo, I
    Monica, CD
    Bifulco, G
    De Riccardis, F
    TETRAHEDRON, 2004, 60 (26) : 5577 - 5586