New carboxylic acid MMP inhibitors derived from a propargyl glycine scaffold.

被引:0
|
作者
Laufersweiler, MJ [1 ]
Natchus, MG [1 ]
Bookland, R [1 ]
机构
[1] Procter & Gamble Pharmaceut, Mason, OH 45040 USA
关键词
D O I
暂无
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
23-MEDI
引用
收藏
页码:U4 / U5
页数:2
相关论文
共 50 条
  • [1] The development of new carboxylic acid-based MMP inhibitors derived from a cyclohexylglycine scaffold
    Tullis, JS
    Laufersweiler, MJ
    VanRens, JC
    Natchus, MG
    Bookland, RG
    Almstead, NG
    Pikul, S
    De, B
    Hsieh, LC
    Janusz, MJ
    Branch, TM
    Peng, SX
    Jin, YY
    Hudlicky, T
    Oppong, K
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2001, 11 (15) : 1975 - 1979
  • [2] Development of new carboxylic acid-based MMP inhibitors derived from functionalized propargylglycines
    Natchus, MG
    Bookland, RG
    Laufersweiler, MJ
    Pikul, S
    Almstead, NG
    De, B
    Janusz, MJ
    Hsieh, LC
    Gu, F
    Pokross, ME
    Patel, VS
    Garver, SM
    Peng, SX
    Branch, TM
    King, SL
    Baker, TR
    Foltz, DJ
    Mieling, GE
    JOURNAL OF MEDICINAL CHEMISTRY, 2001, 44 (07) : 1060 - 1071
  • [3] Potent and selective inhibitors of bacterial methionyl tRNA synthetase derived from an oxazolone-dipeptide scaffold.
    Tandon, M
    Coffen, DL
    Gallant, P
    Finn, J
    Keith, D
    Ashwell, MA
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2004, 227 : U18 - U19
  • [4] New potential anticancer agents based on the anthranilic acid scaffold. Synthesis and evaluation of biological activity
    Congiu, C
    Cocco, MT
    Lilliu, V
    Onnis, V
    JOURNAL OF MEDICINAL CHEMISTRY, 2005, 48 (26) : 8245 - 8252
  • [5] Design and synthesis of new donepezil analogs derived from arylpiperazine scaffold as acetylcholinesterase inhibitors
    Sahin, Zafer
    Biltekin, Sevde Nur
    Buelbuel, Emre Fatih
    Yurttas, Leyla
    Berk, Barkin
    Demirayak, Seref
    PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS, 2020, 196 (03) : 283 - 293
  • [6] Modification of glycine α-ketoamide HCV protease inhibitors:: Effect of carboxylic acid isosteres.
    Han, W
    Hu, ZL
    Jiang, XJ
    Wasserman, ZR
    Gorey-Feret, LJ
    Meek, JL
    Decicco, CP
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2001, 221 : U21 - U21
  • [7] Synthesis and physicochemical study of new surfactants derived from carboxylic acid sugars
    Moon, TL
    Blanzat, M
    Labadie, L
    Perez, E
    Rico-Lattes, I
    JOURNAL OF DISPERSION SCIENCE AND TECHNOLOGY, 2001, 22 (2-3) : 167 - 176
  • [8] Chiral carboxylic acid ligands derived from camphoric acid
    Moloney, MG
    Paul, DR
    Thompson, RM
    Wright, E
    TETRAHEDRON-ASYMMETRY, 1996, 7 (09) : 2551 - 2562
  • [9] Investigation of glycine α-ketoamide HCVNS3 protease inhibitors:: Effect of carboxylic acid isosteres
    Han, W
    Jiang, XJ
    Hu, ZL
    Wasserman, ZR
    Decicco, CP
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2005, 15 (15) : 3487 - 3490
  • [10] Discovery of a New Class of Potent MMP Inhibitors by Structure-Based Optimization of the Arylsulfonamide Scaffold
    Mori, Mattia
    Massaro, Assunta
    Calderone, Vito
    Fragai, Marco
    Luchinat, Claudio
    Mordini, Alessandro
    ACS MEDICINAL CHEMISTRY LETTERS, 2013, 4 (06): : 565 - 569