Malignant lymphoma of the bone associated with systemic sarcoidosis

被引:11
|
作者
Kobayashi, H [1 ]
Kato, Y [1 ]
Hakamada, M [1 ]
Hattori, Y [1 ]
Sato, A [1 ]
Shimizu, N [1 ]
Imamura, A [1 ]
Mihara, H [1 ]
Kato, H [1 ]
Oki, Y [1 ]
Morishita, M [1 ]
Miwa, H [1 ]
Nitta, M [1 ]
机构
[1] Aichi Med Univ, Dept Internal Med 2, Nagakute, Aichi 4801195, Japan
关键词
sarcoidosis-lymphoma syndrome; Ga-67; scintigraphy; HHV-8;
D O I
10.2169/internalmedicine.40.435
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
57-year-old woman was hospitalized with malignant lymphoma of the right talus, After treatment, complete remission was obtained. Gallium-67 scintigraphy to confirm the remission demonstrated increased uptake in the whole body skeletal muscle, especially in her thighs, Biopsy of right gastrocnemius muscle showed epithelioid granuloma, Serum angiotensin-converting enzyme activity (ACE) and lysozyme had increased to several times the normal range. We diagnosed her disease as bone-associated sarcoidosis-lymphoma syndrome. Human herpes virus 8 (HHV-8) genome was examined in the bone marrow specimen, and the relationship between sarcoidosis-lymphoma syndrome and HHV-8 was discussed.
引用
收藏
页码:435 / 438
页数:4
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