Interdisciplinary Management of Perianal Crohn's Disease

被引：6
|
作者：
Lightner, Amy L. [1 ]
Faubion, William A. [2 ]
Fletcher, Joel G. [3 ]
机构：
[1] Mayo Clin, Div Colon & Rectal Surg, 200 1st St Southwest, Rochester, MN 55905 USA
[2] Mayo Clin, Div Gastroenterol, 200 1st St Southwest, Rochester, MN 55905 USA
[3] Mayo Clin, Div Radiol, 200 1st St Southwest, Rochester, MN 55905 USA
来源：
GASTROENTEROLOGY CLINICS OF NORTH AMERICA | 2017年 / 46卷 / 03期
关键词：
Perianal fistulizing disease; Crohn's disease; Combined medical and surgical management; FISTULA-IN-ANO; ENDORECTAL ADVANCEMENT FLAP; COMPLEX ANAL FISTULAS; QUALITY-OF-LIFE; SURGICAL-TREATMENT; ANORECTAL FISTULAS; CLINICAL-TRIAL; DOUBLE-BLIND; DEFINITIVE SURGERY; MYOCUTANEOUS FLAPS;
D O I：
10.1016/j.gtc.2017.05.008
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
Perianal disease is a common manifestation of Crohn's disease (CD) that results in significant morbidity and decreased quality of life. Despite several medical and surgical options, complex perianal CD remains difficult to treat. Before the advent of biologic therapy, antibiotics were the mainstay of medical treatment. Infliximab remains the most well-studied medical therapy for perianal disease. Surgical interventions are limited by the risk of nonhealing wounds and potential incontinence. When treatment options fail, fecal diversion or proctectomy may be necessary. Stem cell therapies may offer improved results and seem to be safe, but are not yet widely used.
引用
收藏
页码：547 / +
页数：18
相关论文
共 50 条
  • [1] Management of perianal Crohn's disease
    Person B.
    Wexner S.D.
    [J]. Current Treatment Options in Gastroenterology, 2005, 8 (3) : 197 - 209
  • [2] Management of Perianal Crohn's Disease
    Parian, Alyssa M.
    Obi, Megan
    Fleshner, Phillip
    Schwartz, David A.
    [J]. AMERICAN JOURNAL OF GASTROENTEROLOGY, 2023, 118 (08): : 1323 - 1331
  • [3] Management of perianal Crohn's disease
    Wise, PE
    Schwartz, DA
    [J]. CLINICAL GASTROENTEROLOGY AND HEPATOLOGY, 2006, 4 (04) : 426 - 430
  • [4] The management of perianal Crohn's disease
    Halverson, Amy
    [J]. AMERICAN JOURNAL OF GASTROENTEROLOGY, 2007, 102 : S85 - S87
  • [5] The management of perianal Crohn's disease
    Frizelle, FA
    Santoro, GA
    Pemberton, JH
    [J]. INTERNATIONAL JOURNAL OF COLORECTAL DISEASE, 1996, 11 (05) : 227 - 237
  • [6] Management of perianal Crohn's disease
    Hanauer, SB
    [J]. Inflammatory Bowel Disease: Translation From Basic Research to Clinical Practice, 2005, 140 : 234 - 239
  • [7] THE ROLE OF INTERDISCIPLINARY MANAGEMENT OF COMPLEX PERIANAL FISTULAS IN CROHN'S DISEASE: AN UNRESOLVED ISSUE
    Maestri, S.
    Scrivo, B.
    Giuffrida, E.
    Fontana, T.
    Falco, N.
    Peralta, S.
    Lo Re, G.
    Cocorullo, G.
    Cappello, M.
    [J]. DIGESTIVE AND LIVER DISEASE, 2019, 51 : E231 - E232
  • [8] Management of Perianal Fistulas in Crohn's Disease
    Seyfried, Steffen
    Herold, Alexander
    [J]. VISCERAL MEDICINE, 2019, 35 (06) : 338 - 342
  • [9] Current management of perianal Crohn's disease
    Mahmoud, Najjia N.
    Halwani, Yasmin
    de Montbrun, Sandra
    Shah, Puja M.
    Hedrick, Traci L.
    Rashid, Farzana
    Schwartz, David A.
    Dalal, Robin L.
    Kaminski, Jan P.
    Zaghiyan, Karen
    Fleshner, Phillip R.
    Weissler, Jason M.
    Fischer, John P.
    [J]. CURRENT PROBLEMS IN SURGERY, 2017, 54 (05) : 262 - 298
  • [10] Management of perianal disease in patients with Crohn's disease
    Algaba, A.
    Rubin de Celix, C.
    Guerra, I.
    Serrano, A.
    Perez-Viejo, E.
    Aullo, C.
    Hernandez-Tejero, M.
    Granja, A.
    Bermejo, F.
    [J]. JOURNAL OF CROHNS & COLITIS, 2017, 11 : S236 - S237
12345