Synthesis and Herbicidal Activity of 5-(4-Hydroxybenzyl)-2-Thioxoimidazolidin-4-one Esters

被引：20

作者：

Han, Jintao ^{[1
]}

Wang, Jinmin ^{[1
]}

Dong, Hongbo ^{[1
]}

Lei, Jianping ^{[1
]}

Wang, Mingan ^{[1
,2
]}

Fang, Jianxin ^{[2
]}

机构：

[1] China Agr Univ, Dept Appl Chem, Beijing 100193, Peoples R China

[2] Nankai Univ, State Key Lab Elementoorgan Chem, Tianjin 300071, Peoples R China

来源：

MOLECULES | 2011年 / 16卷 / 04期

关键词：

5-(4-hydroxybenzyl)-2-thioxoimidazolidin-4-one esters; synthesis; herbicidal activity; ADENYLOSUCCINATE SYNTHETASE; BIOLOGICAL-ACTIVITIES; HYDANTOCIDIN; INHIBITOR; MECHANISM; SITE;

D O I：

10.3390/molecules16042833

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A series of novel 5-(4-hydroxybenzyl)-2-thioxoimidazolidin-4-one esters were synthesized under mild conditions by the reaction of 5-(4-hydroxybenzyl)-2-thioxoimidazolidin-4-one and carboxylic acids with DCC and DMAP as the promoters. Their structures were confirmed by H-1-NMR, IR, ESI-MS and elemental analysis. The preliminary bioassy results indicated that some of compounds exhibit good herbicidal activity against Zea mays, Triticum aestivum and Arabidopsis thaliana. The further greenhouse test showed that compounds 6-16 and 6-28 have 60%, 50% and 50% efficacy against Stellaria media, Echinochloa crus-galli and Setaria viridis at 1,000 g/ha, respectively.

引用

页码：2833 / 2845

页数：13

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