Sensitivity of the Elecsys Nucleocapsid Assay for the Detection of Preceding SARS-CoV-2 Infections

被引：5
|
作者：
Grunau, Brian [1 ,2 ,3 ]
Tom, Janessa [3 ]
Asamoah-Boaheng, Michael [2 ,4 ]
O'Brien, Sheila F. [5 ]
Drews, Steven J. [5 ,6 ]
Sediqi, Sadaf [7 ]
Lavoie, Pascal M. [8 ]
Barakauskas, Vilte [7 ]
Goldfarb, David M. [7 ]
机构：
[1] St Pauls Hosp, Ctr Hlth Evaluat & Outcome Sci, Vancouver, BC, Canada
[2] Univ British Columbia, Dept Emergency Med, Vancouver, BC, Canada
[3] British Columbia Emergency Hlth Serv, Vancouver, BC, Canada
[4] Mem Univ Newfoundland, Fac Med, St John, NF, Canada
[5] Canadian Blood Serv, Ottawa, ON, Canada
[6] Univ Alberta, Lab Med & Pathol, Edmonton, AB, Canada
[7] Univ British Columbia, Dept Pathol & Lab Med, Vancouver, BC, Canada
[8] Univ British Columbia, Dept Pediat, Vancouver, BC, Canada
来源：
OPEN FORUM INFECTIOUS DISEASES | 2022年 / 9卷 / 08期
关键词：
SARS-CoV-2; COVID-19; vaccine; antibodies; nucleocapsid;
D O I：
10.1093/ofid/ofac349
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Nucleocapsid serological assay sensitivity to identify severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections among vaccinees and for Omicron cases is unclear. In this prospective study, the Elecsys nucleocapsid assay was 89% sensitive in identifying SARS-CoV-2 infections 14-607 days pre-blood collection. Sensitivity was similar when comparing by vaccination status, and in Omicron (vs pre-Omicron) cases.
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页数：4
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