Syntheses, Crystal Structures and Properties of Zn(II) and Cd(II) Complexes with Acylhydrazone Schiff Base

The complexes of hydrazone Schiff base, [M(HBrsth)(2)](M=Zn (1), Cd (2)) and [Cd(L)(2)] (3), where H(2)Brsth is 2-thiophenecarboxylic acid (2-hydroxly-5-bromo-benzylidene)-hydrazide, HL is pyridine-4-carboxylic acid (pyridine-2-yl ethylidyne)-hydrazide, were respectively synthesized by slow evaporation methods in mixed-solvent, and characterized by elemental analysis, IR, UV-Vis, FL spectra and TGA. The structure of 1 and 3 has been accomplished by single crystal X-ray diffraction, which results confirm that the crystal of 1 belongs to the monoclinic system, space group C2/c with cell parameters a=2.315 4(4) nm, b=0.603 0(1) nm, c=1.911 2(4) nm, beta=108.5(3)degrees and the crystal of 3 belongs to the orthorhombic system, space group C2cb with cell parameters a=0.988 6(2) nm, b=1.950 2(4) nm, c=1.244 0(2) nm. The antitumor activities in vitro against HEPG2 and SW620 cancer cells lines of complexes were tested by MTT method. In addition, fluorescent properties of three complexes were investigated. CCDC: 1432467, 1; 1450427, 3.