Synthesis and Antimicrobial Activity of Some 7-Aryl-5,6-dihydro-14aza[1]benzopyrano[3,4-b]phenanthren-8H-ones

被引：11
|
作者：
Brahmbhatt, Dinker I. [1 ]
Patel, Niraj H. [1 ]
Patel, Anil K. [1 ]
Patel, Mehul A. [1 ]
Patel, Varun G. [1 ]
机构：
[1] Sardar Patel Univ, Dept Chem, Vallabh Vidyanagar 388120, Gujarat, India
来源：
JOURNAL OF HETEROCYCLIC CHEMISTRY | 2011年 / 48卷 / 04期
关键词：
HETEROCYCLES; COUMARINS;
D O I：
10.1002/jhet.648
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The title compounds, 7-aryl-5,6-dihydro-14-aza[1]benzopyrano[3,4-b]phenanthren-8H-ones 3a-l have been synthesized by reacting various 4-hydroxy coumarins 1a-c with 2-arylidene-1-tetralones 2a-d in the presence of ammonium acetate and acetic acid under Krohnke's reaction condition. The structures of all the synthesized compounds were supported by analytical, IR, H-1-NMR, and C-13-NMR data. All the synthesized compounds 3a-l have been screened for their antibacterial activities against Escherichia coli (Gram -ve bacteria), Bacillus subtilis (Gram +ve bacteria), and antifungal activity against Candida albicans (Fungi).
引用
收藏
页码：840 / 844
页数：5
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