A mysterious case of recurrent fracture: Tumour-induced osteomalacia

被引:0
|
作者
Shetty, Sahana [1 ]
Ravindra, Shruthi [1 ]
Acharya, Himamshu [1 ]
Rao, Sharath K. [2 ]
机构
[1] Manipal Acad Higher Educ, MAHE, Kasturba Med Coll, Dept Endocrinol, Manipal 576104, Karnataka, India
[2] Manipal Acad Higher Educ, MAHE, Kasturba Med Coll, Dept Orthopaed, Manipal, Karnataka, India
关键词
FGF-23; hypophosphatemia; tumour-induced osteomalacia; HYPOPHOSPHATEMIC OSTEOMALACIA; ONCOGENIC OSTEOMALACIA; PHOSPHATE-TRANSPORT; FGF-23; GENES; FGF23; BONE;
D O I
10.4103/jfmpc.jfmpc_947_21
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
We report a case of tumour-induced osteomalacia in a 59-year-old man who presented with a long-standing history of myalgia, bone pain and pathological fracture of the bilateral femur at different intervals in the past 4 years. A biochemical evaluation revealed hypophosphatemia secondary to phosphaturia. Localization study by Ga-68 DOTANOC PET-CT for adult-onset hypophosphatemic osteomalacia revealed a tumour in the right femoral head. Resection of the tumour resulted in clinical improvement as well as normalization of biochemical parameters.
引用
收藏
页码:1204 / 1207
页数:4
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