Comparative modeling of C1 regulatory domains in the protein kinase C isozyme family.

被引:0
|
作者
Peach, ML
Nicklaus, MC
Blumberg, PM
Marquez, VE
机构
[1] NCI, Med Chem Lab, NIH, Ft Detrick, MD 21702 USA
[2] NCI, Cellular Carcinogenesis & Tumor Promot Lab, NIH, Bethesda, MD 20892 USA
关键词
D O I
暂无
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
188-COMP
引用
收藏
页码:U761 / U761
页数:1
相关论文
共 50 条
  • [1] Taxonomy and function of C1 protein kinase C homology domains
    Hurley, JH
    Newton, AC
    Parker, PJ
    Blumberg, PM
    Nishizuka, Y
    [J]. PROTEIN SCIENCE, 1997, 6 (02) : 477 - 480
  • [2] Maturation of protein kinase C masks its C1 domains
    Antal, Corina Elena
    Skovso, Sos
    Newton, Alexandra C.
    [J]. FASEB JOURNAL, 2012, 26
  • [3] Asymmetric activator binding to the C1 domains of protein kinase C alpha
    Chappell, Lucy
    Slater, Simon J.
    [J]. BIOPHYSICAL JOURNAL, 2007, : 447A - 447A
  • [4] Diacylglycerol Lactones Targeting the Structural Features That Distinguish the Atypical C1 Domains of Protein Kinase C ζ and ι from Typical C1 Domains
    Pu, Yongmei
    Kang, Ji-Hye
    Sigano, Dina M.
    Peach, Megan L.
    Lewin, Nancy E.
    Marquez, Victor E.
    Blumberg, Peter M.
    [J]. JOURNAL OF MEDICINAL CHEMISTRY, 2014, 57 (09) : 3835 - 3844
  • [5] Establishment of a binding assay for protein kinase C isozymes using synthetic C1 peptides and development of new medicinal leads with protein kinase C isozyme and C1 domain selectivity
    Irie, K
    Nakahara, A
    Nakagawa, Y
    Ohigashi, H
    Shindo, M
    Fukuda, H
    Konishi, H
    Kikkawa, U
    Kashiwagi, K
    Saito, N
    [J]. PHARMACOLOGY & THERAPEUTICS, 2002, 93 (2-3) : 271 - 281
  • [6] The C1 and C2 domains of protein kinase C are independent membrane targeting modules, with specificity for phosphatidylserine conferred by the C1 domain
    Johnson, JE
    Giorgione, J
    Newton, AC
    [J]. BIOCHEMISTRY, 2000, 39 (37) : 11360 - 11369
  • [7] Inhibitory properties of the regulatory domains of human protein kinase Cα and mouse protein kinase Cε
    Parissenti, AM
    Kirwan, AF
    Kim, SA
    Colantonio, CM
    Schimmer, BP
    [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 1998, 273 (15) : 8940 - 8945
  • [8] Protein kinase C inhibits type VI adenylyl cyclase by phosphorylating the regulatory N domain and two catalytic C1 and C2 domains
    Lin, TH
    Lai, HL
    Kao, YY
    Sun, CN
    Hwang, MJ
    Chern, YJ
    [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 2002, 277 (18) : 15721 - 15728
  • [9] Interplay of C1 and C2 domains of protein kinase C-α in its membrane binding and activation
    Medkova, M
    Cho, WH
    [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 1999, 274 (28) : 19852 - 19861
  • [10] Synthesis and functional analysis of the cysteine-rich domains of protein kinase C (PKC) for development of new medicinal leads with PKC isozyme and C1 domain selectivity
    Irie, K
    Ohigashi, H
    [J]. JOURNAL OF SYNTHETIC ORGANIC CHEMISTRY JAPAN, 2002, 60 (06) : 563 - 572