Highly convenient, one-pot synthesis of nitriles from aldehydes using the NH2OH•HCl/NaI/MeCN system

被引：32
|
作者：
Ballini, R [1 ]
Fiorini, D [1 ]
Palmieri, A [1 ]
机构：
[1] Univ Camerino, Dipartimento Sci Chim, I-62032 Camerino, Italy
来源：
SYNLETT | 2003年 / 12期
关键词：
aldehydes; hydroxylamine hydrochloride; sodium iodide; catalysis; nitriles;
D O I：
10.1055/s-2003-41408
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Direct transformation of both aliphatic and aromatic aldehydes to the corresponding nitrites, can be easily performed by the reaction of an aldehyde with a slight excess of hydroxylamine hydrochloride. in refluxing acetonitrile and in the presence of 0.5 equivalents of sodium iodide as catalyst.
引用
收藏
页码：1841 / 1843
页数：3
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