This study aimed to perform a comparative assessment of microleakage in Class V cavities among five different composite resins For this purpose 100 fresh caries-free human permanent molars were randomly assigned to one of five groups (n=20) Clearfil Majesty Esthetic + Clearfil S3 Bond (Group I) TPH Spectrum + Xeno V (Group II) Gradia Direct Anterior + G Bond (GC) (Group III) Premise + Optibond All in One (Group IV) and Charisma + iBond (Group V) were applied and polymerized under LED Specimens were varnished immersed in 0 5% methylene and sectioned bucco-palatinally/lingually and microleakage scores were determined Gingival and occlusal microleakage scores among groups were statistically significant (p < 0 05) (p=0 043 p=0 005) Occlusal microleakage scores for Clearfil Majesty Esthetic and Premise were lower than in the other groups Charisma had the highest microleakage scores with no difference among the other groups (p > 0 05) In conclusion occlusal and gingival microleakage scores were satisfactory except for Charisma