Detection of antiretroviral resistance in HIV-1

被引:0
|
作者
Cavert, W
Balfour, HH
机构
[1] Univ Minnesota, Dept Med, Minneapolis, MN 55455 USA
[2] Univ Minnesota, Dept Lab Med, Minneapolis, MN 55455 USA
[3] Univ Minnesota, Dept Pathol, Minneapolis, MN 55455 USA
[4] Univ Minnesota, Dept Pediat, Minneapolis, MN 55455 USA
关键词
D O I
10.1016/S0272-2712(03)00083-0
中图分类号
R446 [实验室诊断]; R-33 [实验医学、医学实验];
学科分类号
1001 ;
摘要
Resistance testing should be readily available to every clinician who specializes in HIV/AIDS. There are two main methods for HIV-1 resistance testing: genotyping and phenotyping. Selecting an initial antiretroviral treatment regimen or changing a failing one according to the test results is complex and requires knowledgeable interpretation to maximize the clinical benefit. To aid interpretation of resistance data, tables are provided with known resistance mutations and cutoff values for phenotypic resistance.
引用
收藏
页码:915 / +
页数:15
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