Denaturing high performance liquid chromatography a novel technique for detection of genetic mutation/polymorphisms

被引:0
|
作者
Fang, NH [1 ]
Lin, L [1 ]
Ren, JC [1 ]
Wu, D [1 ]
机构
[1] Shanghai Jiao Tong Univ, Dept Chem, Shanghai 200240, Peoples R China
关键词
denaturing high performance liquid chromatography; genetic mutation; detection;
D O I
暂无
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Denaturing high performance liquid chromatography (DHPLC) has been successfully used for the genetic mutation/polymorphisms analysis. Compared with conventional slab gel electrophoresis, this technique is sensitive, effective and economical. The fundamental aspects and the development of the applications of this technique in recent years are reviewed.
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页码:343 / 349
页数:7
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