Glossary of terms used in biomolecular screening (IUPAC Recommendations 2011)

被引：4

作者：

Proudfoot, John ^{[1
]}

Nosjean, Olivier ^{[2
]}

Blanchard, Jan ^{[3
]}

Wang, John ^{[4
]}

Besson, Dominique ^{[5
]}

Crankshaw, Denis ^{[6
]}

Gauglitz, Guenter ^{[7
]}

Hertzberg, Robert ^{[8
]}

Homon, Carol ^{[1
]}

Llewellyn, Lyndon ^{[9
]}

Neubig, Richard ^{[10
]}

Walker, Larry ^{[11
]}

Villa, Pascal ^{[12
]}

机构：

[1] Boehringer Ingelheim Pharmaceut Inc, Ridgefield, CT 06877 USA

[2] Servier Res Inst, F-78290 Croissy Sur Seine, France

[3] McMaster Univ, Dept Biochem & Biomed Sci, McMaster HTS Lab, Hamilton, ON L8N 3Z5, Canada

[4] AJLW Consulting Inc, Oakland, CA 94619 USA

[5] WHO, TDR, Special Programme Res & Training Neglected Dis, CH-1211 Geneva, Switzerland

[6] McMaster Univ, Dept Obstet & Gynecol, Hamilton, ON L8N 3Z5, Canada

[7] Univ Tubingen, Inst Phys & Theoret Chem, D-72076 Tubingen, Germany

[8] GlaxoSmithKline, King Of Prussia, PA 19406 USA

[9] Australian Inst Marine Sci, Townsville, Qld 4810, Australia

[10] Univ Michigan, Dept Pharmacol, Ann Arbor, MI 48109 USA

[11] Univ Mississippi, Natl Ctr Nat Prod Res, University, MS 38677 USA

[12] IFR 85 Biomol & Innovat Therapeut, F-67401 Illkirch Graffenstaden, France

来源：

PURE AND APPLIED CHEMISTRY | 2011年 / 83卷 / 05期

关键词：

assay types; biomolecular screening; data handling; drug discovery; glossary; IUPAC Chemistry and Human Health Division; CHEMISTRY; NOMENCLATURE; EDITION;

D O I：

10.1351/PAC-REC-09-05-03

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Biomolecular screening is now a crucial component of the drug discovery process, and this glossary will be of use to practitioners in the field of screening and to those who interact with the screening community. The glossary contains definitions related to various aspects of the screening process such as assay types, data handling, and relevant technologies. Many of the terms used in this discipline are not covered by existing glossaries, and where they are, the definitions are often not appropriate for this field. Where appropriate, this document provides new or modified definitions to better reflect the new context. The field of biomolecular screening is multidisciplinary in nature, and this glossary, containing authoritative definitions, will be useful not only for regular practitioners, but also for those who make use of data generated during the screening process.

引用

页码：1129 / 1158

页数：30

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