Speckle reduction in optical coherence tomography images using tissue viscoelasticity

被引：19

作者：

Kennedy, Brendan F. ^{[1
]}

Curatolo, Andrea ^{[1
]}

Hillman, Timothy R. ^{[4
]}

Saunders, Christobel M. ^{[2
,5
]}

Sampson, David D. ^{[1
,3
]}

机构：

[1] Univ Western Australia, Sch Elect Elect & Comp Engn, Opt Biomed Engn Lab, Crawley, WA 6009, Australia

[2] Univ Western Australia, Sch Surg, Crawley, WA 6009, Australia

[3] Univ Western Australia, Ctr Microscopy Characterisat & Anal, Crawley, WA 6009, Australia

[4] MIT, George R Harrison Spect Lab, Cambridge, MA 02139 USA

[5] Sir Charles Gairdner Hosp, Nedlands, WA 6009, Australia

来源：

JOURNAL OF BIOMEDICAL OPTICS | 2011年 / 16卷 / 02期

关键词：

optical coherence tomography; speckle reduction; viscoelasticity;

D O I：

10.1117/1.3548239

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

We present a technique to reduce speckle in optical coherence tomography images of soft tissues. An average is formed over a set of B-scans that have been decorrelated by viscoelastic creep strain. The necessary correction for the deformation-induced spatial distortions between B-scans is achieved through geometrical co-registration using an affine transformation. Speckle reduction by up to a factor of 1.65 is shown in images of tissue-mimicking soft fibrin phantoms and excised human lymph node tissue with no observable loss of spatial resolution. (C) 2011 Society of Photo-Optical Instrumentation Engineers (SPIE). [DOI:10.1117/1.3548239]

引用

页数：3

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