Genomewide Association Studies in Pharmacogenomics: Meeting Report of the NIH Pharmacogenomics Research Network-RIKEN (PGRN-RIKEN) Collaboration

被引：7

作者：

Yee, S. W. ^{[1
]}

Momozawa, Y. ^{[1
]}

Kamatani, Y. ^{[1
]}

Tyndale, R. F. ^{[1
]}

Weinshilboum, R. M. ^{[1
]}

Ratain, M. J. ^{[1
]}

Giacomini, K. M. ^{[1
]}

Kubo, M. ^{[1
]}

机构：

[1] Univ Calif San Francisco, Dept Bioengn & Therapeut Sci, San Francisco, CA 94143 USA

来源：

CLINICAL PHARMACOLOGY & THERAPEUTICS | 2016年 / 100卷 / 05期

关键词：

WIDE ASSOCIATION;

D O I：

10.1002/cpt.405

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Genomewide association studies (GWAS) have resulted in the identification of many heritable genetic factors that underlie risk for human disease or variation in physiologic traits. In contrast, there are fewer GWAS of drug response phenotypes, despite extensive unexplained interindividual variability. To address this urgent need, the NIH Pharmacogenomics Research Network (PGRN) and the Center for Integrative Medical Sciences (IMS) at RIKEN support a collaboration, PGRN-RIKEN, with the goal of accelerating GWAS of drug response phenotypes.

引用

页码：423 / 426

页数：4

共 4 条

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