Management of hypertensive crises in the elderly

被引:11
|
作者
Alshami, Abbas [1 ,2 ]
Romero, Carlos [1 ,3 ]
Avila, America [1 ,4 ]
Varon, Joseph [5 ,6 ,7 ]
机构
[1] Dorrington Med Associates, Houston, TX USA
[2] Univ Baghdad, Coll Med, Baghdad, Iraq
[3] Univ Autonoma San Luis Potosi, San Luis Potosi, Mexico
[4] Univ Durango Santander, Hermosillo, Sonora, Mexico
[5] Univ Texas Hlth Sci Ctr Houston, 2219 Dorrington St, Houston, TX 77030 USA
[6] Univ Texas Med Branch Galveston, Galveston, TX USA
[7] United Gen Hosp, United Mem Med Ctr, Crit Care Serv, Houston, TX USA
关键词
Beta-blockers; Calcium channel blockers; Clevidipine; Elderly; Esmolol; Fenoldopam; Hypertensive crises; Labetalol; Nicardipine; Nitroprusside; ACTING CALCIUM-ANTAGONIST; CARDIAC-SURGERY PATIENTS; SODIUM-NITROPRUSSIDE; BLOOD-PRESSURE; PERIOPERATIVE HYPERTENSION; INTRAVENOUS NICARDIPINE; CLINICAL-EVALUATION; PRACTICE PATTERNS; DRUG-THERAPY; DOUBLE-BLIND;
D O I
10.11909/j.issn.1671-5411.2018.07.007
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Hypertensive crises are elevations of blood pressure higher than 180/120 mmHg. These can be urgent or emergent, depending on the presence of end organ damage. The clinical presentation of hypertensive crises is quite variable in elderly patients, and clinicians must be suspicious of non-specific symptoms. Managing hypertensive crises in elderly patients needs meticulous knowledge of the pathophysiological changes in them, pharmacological options, pharmacokinetics of the medications used, their side effects, and their interactions with other medications. Clevidipine, nicardipine, labetalol, esmolol, and fenoldopam are among the preferred choices in the elderly due to their efficacy and tolerability. Nitroprusside, hydralazine, and nifedipine should be avoided, unless there are no other options available, due to the high risk of complications and unpredictable responses.
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页码:504 / 512
页数:9
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