Viscoelastic and swelling properties of glucose oxidase loaded polyacrylamide hydrogels and the evaluation of their properties as glucose sensors

被引：76
|
作者：
Fernández, E
López, D
López-Cabarcos, E
Mijangos, C
机构：
[1] CSIC, Inst Ciencia & Tecnol Polimeros, Madrid 28006, Spain
[2] UCM, Fac Farm, Dept Quim Fis, Madrid 28040, Spain
来源：
POLYMER | 2005年 / 46卷 / 07期
关键词：
polyacrylamide hydrogels; viscoelastic properties; glucose biosensor;
D O I：
10.1016/j.polymer.2004.12.039
中图分类号：
O63 [高分子化学（高聚物）];
学科分类号：
070305 ; 080501 ; 081704 ;
摘要：
Here we report the immobilization of glucose oxidase in polyacrylamide hydrogels carried out by aqueous crosslinking copolymerization of acrylamide and N,N' methylene bisacrylamide in the presence of the enzyme. The swelling and viscoelastic properties of the hydrogels were evaluated as a function of the content of crosslinker of the polymer chains and enzyme concentration. Amperometric measurements were also carried out to evaluate the system as a glucose biosensor. (c) 2004 Elsevier Ltd. All rights reserved.
引用
收藏
页码：2211 / 2217
页数：7
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