Condensed Bridgehead Nitrogen Heterocyclic System: Microwave Assisted Synthesis and Bioactivity of s-Triazolo[3,4-b][1,3,4]thiadiazoles, s-Triazolo[3,4-b][1,3,4]thiadiazines and s-Triazolo [3′,4′:2,3]thiadiazino[5,6-b]quinoxaline

被引：0

作者：

Raju, R. R. R. K. ^{[2
]}

Reddy, T. M. ^{[3
]}

Chakravarthy, A. K. ^{[1
]}

机构：

[1] Dr Reddys Labs Ltd, IPDO, Hyderabad 500123, Andhra Pradesh, India

[2] Jubiliant Chemsys Ltd, Sector 58, Noida 201301, India

[3] Kakatiya Inst Technol & Sci, Dept Phys Sci, Warangal 506015, Andhra Pradesh, India

来源：

ASIAN JOURNAL OF CHEMISTRY | 2011年 / 23卷 / 01期

关键词：

Nitrogen; Heterocyclic compounds; Quinoxaline;

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

N-[3-(4-Amino-5-mercapto-4H-[1,2,3]triazol-3-yl)-4,5,6,7-tetrahydro-benzo[b] thiophen-2-yl]benzamide (1) on condensation with chloroacetic acid, alpha-haloketone and benzoin furnishes (1,2,4]triazolo[3,4-b][1,3,4]thiadiazine derivatives (2), (3) and (4) respectively, while condensation with 2,3-dichloroquinoxaline, carbon disulphide, aromatic carboxylic acid and aromatic carboxaldehydes yield the cyclic products, [1,2,4] triazolo[3,4-b][1,3,4]thiadiazole derivatives (5), (6), (7), (8) respectively. The compounds have been characterized on the basis of elemental analysis and spectral data. The antibacterial, antifungal and antitubercular activities of the compounds have also been evaluated.

引用

页码：444 / 446

页数：3

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