Motivated by studies warning about a possible re-emergence of poliomyelitis in Europe, we analyse a compartmental model for the transmission of polio describing the possible effect of unvaccinated people arriving to a region with low vaccination coverage. We calculate the basic reproduction number, and determine the global dynamics of the system: we show that, depending on the parameters, one of the two equilibria is globally asymptotically stable. The main tools applied are Lyapunov functions and persistence theory. We illustrate the analytic results by numerical examples, which also suggest that in order to avoid the risk of polio re-emergence, vaccinating the immigrant population might result insufficient, and also the vaccination coverage of countries with low rates should be increased. (C) 2017 Elsevier Inc. All rights reserved.
机构:
Uppsala Univ, Dept Med Chem, Fac Pharm, S-75123 Uppsala, Sweden
Univ Cent Punjab, Fac Pharm, Lahore, PakistanDow Univ Hlth Sci, Dow Med Coll, Dept Internal Med, Karachi, Pakistan
Butt, Muhammad Hammad
Ullah, Irfan
论文数: 0引用数: 0
h-index: 0
机构:
Gandhara Univ, Kabir Med Coll, Peshawar, Pakistan
Khyber Med Univ, IPH&SS, Peshawar, PakistanDow Univ Hlth Sci, Dow Med Coll, Dept Internal Med, Karachi, Pakistan