Electrophysiological indices associated with social functioning outcome in schizophrenia: a 5-year follow-up study

被引：4

作者：

Maeda, K ^{[1
]}

Nakagome, K ^{[1
]}

Kasai, K ^{[1
]}

Ikebuchi, E ^{[1
]}

Iwanami, A ^{[1
]}

Kudoh, N ^{[1
]}

Araki, T ^{[1
]}

Fukuda, M ^{[1
]}

机构：

[1] Univ Tokyo, Grad Sch Med, Dept Neuropsychiat, Bunkyo Ku, Tokyo 1138655, Japan

来源：

NEUROSCIENCE RESEARCH | 2005年 / 51卷 / 02期

关键词：

schizophrenia; event-related potentials; N2b; social functioning; quality of life scale;

D O I：

10.1016/j.neures.2004.11.001

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

We previously demonstrated that event-related potentials (ERPs), such as N1/N2b amplitudes in an auditory selective attention task, were significantly associated with communication skills of schizophrenia. The present study investigated the relationship between N1/N2b amplitudes and the quality of life (QOL) 5 years after ERP measurement. QOL of 15 patients with schizophrenia was assessed using the quality of life scale (QLS). Correlational analyses revealed a significant relationship between N2b, but not NI, amplitude and specific domains of QOL. N2b amplitude, an electrophysiological index of orienting response, may be associated with longitudinal social functioning outcome in schizophrenia. (C) 2004 Elsevier Ireland Ltd and the Japan Neuroscience Society. All rights reserved.

引用

页码：215 / 218

页数：4

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