FHA Domain pThr Binding Specificity: It's All about Me

被引：7

作者：

Coquelle, Nicolas ^{[1
]}

Glover, J. N. Mark ^{[1
]}

机构：

[1] Univ Alberta, Dept Biochem, Sch Mol & Syst Med, Edmonton, AB T6G 2H7, Canada

来源：

STRUCTURE | 2010年 / 18卷 / 12期

关键词：

RECOGNITION; MOTIF;

D O I：

10.1016/j.str.2010.11.005

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The FHA domain is a phospho-peptide binding module involved in a wide range of cellular pathways, with a striking specificity for phospho-threonine over phospho-serine binding partners. Biochemical, structural, and dynamic simulations analysis allowed Pennell and colleagues to unravel the molecular basis of FHA domain phospho-threonine specificity.

引用

页码：1549 / 1550

页数：2

共 50 条

[1] Structural Delineation of MDC1-FHA Domain Binding with CHK2-pThr68
Wu, Hsin-Hui
Wu, Pei-Yu
Huang, Kai-Fa
Kao, Yu-Ya
Tsai, Ming-Daw
BIOCHEMISTRY, 2012, 51 (02) : 575 - 577
[2] It's All About "Me"
Martinez, Monica
PHI DELTA KAPPAN, 2009, 91 (02) : 74 - 75
[3] It's all about me
Kaiser, Jocelyn
SCIENCE, 2007, 318 (5858) : 1843 - 1843
[4] It's Not All About Me
Parker, Eleanor
HISTORY TODAY, 2018, 68 (01) : 106 - 107
[5] It's all about Me
Dickenson, Donna
NEW SCIENTIST, 2013, 219 (2934) : 26 - 27
[6] FHA: A signal transduction domain with diverse specificity and function
Tsai, MD
STRUCTURE, 2002, 10 (07) : 887 - 888
[7] The molecular basis of FHA Domain:Phosphopeptide binding specificity and implications for phospho-dependent signaling mechanisms
Durocher, D
Taylor, IA
Sarbassova, D
Haire, LF
Westcott, SL
Jackson, SP
Smerdon, SJ
Yaffe, MB
MOLECULAR CELL, 2000, 6 (05) : 1169 - 1182
[8] It's All About "Me" (Behold the Leader)
Billow, Richard M.
INTERNATIONAL JOURNAL OF GROUP PSYCHOTHERAPY, 2012, 62 (04) : 531 - 556
[9] 'It's all about me!': Was that the patient speaking?
Deakin, Anita
Howes, Marten
EMERGENCY MEDICINE AUSTRALASIA, 2016, 28 (06) : 755 - 756
[10] All about ME
Spinney, Laura
NEW SCIENTIST, 2012, 214 (2862) : 44 - 47

← 1 2 3 4 5 →