Scalp and cranial bone metastasis of endometrial carcinoma: A case report and literature review

Objective. The aim of this study is to report a rare case of scalp and cranial bone metastasis of endometrial carcinoma and review the literature. Method. We report a 45-year-old multiparous woman with FIGO Stage 1A Grade II endometrial adenocarcinoma who presented 3 years following total abdominal hysterectomy and bilateral salpingo-oophorectomy with scalp and cranial bone metastasis, Similar cases in the literature are reviewed. Results. The patient metastatic workup revealed local, distant, scalp, and cranial bone metastasis. She died within 6 months. The poor prognosis is similar to that of six other cases reviewed. Conclusion. Scalp and cranial bone metastasis following endometrial carcinoma is extremely rare. It is a reflection of a widely disseminated disease and poor prognosis. However, single bone metastasis has a better postmetastatic survival with the help of local radiotherapy than scalp and multiple bone metastasis. (C) 2001 Academic Press.