Diagnostic imaging, treatment and outcome in a 14-month-old Dobermann with brainstem gemistocytic astrocytoma

被引:1
|
作者
Manzanedo-Delgado, Alba [1 ]
Mason, Sarah [2 ]
Pumarola, Marti [3 ]
Stabile, Fabio [1 ]
机构
[1] Southfields Vet Specialists, Dept Neurol Neurosurg, Basildon, England
[2] Southfields Vet Specialists, Dept Oncol & Radiol, Basildon, England
[3] Autonomous Univ Barcelona, Unit Murine & Comparat Pathol UPMIC, Fac Vet, Barcelona, Spain
来源
VETERINARY RECORD CASE REPORTS | 2021年 / 9卷 / 04期
关键词
magnetic resonance imaging (MRI); neuroimaging; neurology; neuropathology; oncology; radiotherapy; ANAPLASTIC ASTROCYTOMA; SURVIVAL; OLIGOASTROCYTOMA; RADIOTHERAPY; NEOPLASIA; FEATURES; ONCOLOGY; GLIOMA; TUMORS; DOGS;
D O I
10.1002/vrc2.202
中图分类号
S85 [动物医学(兽医学)];
学科分类号
0906 ;
摘要
A 14-month-old male neutered Dobermann presented for investigations into lingual paresis, dysphagia and proprioceptive ataxia of the pelvic limbs. Magnetic resonance imaging (MRI) revealed a mass lesion in the brainstem. Treatment with glucocorticoids and radiation therapy (RT) achieved a good quality of life for 6 months after which deterioration occurred. Repeated MRI revealed an expansion of the mass lesion after which the owners elected for the patient to be euthanised. Post-mortem histological examination and immunohistochemistry confirmed the presence of a gemistocytic astrocytoma. This case report describes the first case in the veterinary literature of a young dog with a brainstem gemistocytic astrocytoma treated with RT and glucocorticoids, with remission of clinical signs and excellent quality of life for 6 months after treatment.
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页数:6
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