Whole-Genome Sequencing of Mexican Strains of Anaplasma marginale: An Approach to the Causal Agent of Bovine Anaplasmosis

被引:8
|
作者
Martinez-Ocampo, Fernando [1 ]
Quiroz-Castaneda, Rosa Estela [2 ]
Amaro-Estrada, Itzel [2 ]
Dantan-Gonzalez, Edgar [1 ]
de la Torre, Jesus Francisco Preciado [2 ]
Rodriguez-Camarillo, Sergio [2 ]
机构
[1] Univ Autonoma Estado Morelos, Ctr Invest Biotecnol, Lab Estudios Ecogen, Cuernavaca 62209, Morelos, Mexico
[2] INIFAP, Ctr Nacl Invest Disciplinaria Salud Anim & Inocui, Unidad Anaplasmosis, Jiutepec 62574, Morelos, Mexico
关键词
QUALITY ASSESSMENT; ALIGNMENT; ALGORITHM;
D O I
10.1155/2020/5902029
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Anaplasma marginale is the main etiologic agent of bovine anaplasmosis, and it is extensively distributed worldwide. We have previously reported the first genome sequence of a Mexican strain of A. marginale (Mex-01-001-01). In this work, we report the genomic analysis of one strain from Hidalgo (MEX-14-010-01), one from Morelos (MEX-17-017-01), and two strains from Veracruz (MEX-30-184-02 and MEX-30-193-01). We found that the genome average size is 1.16-1.17 Mbp with a GC content close to 49.80%. The genomic comparison reveals that most of the A. marginale genomes are highly conserved and the phylogeny showed that Mexican strains cluster with Brazilian strains. The genomic information contained in the four draft genomes of A. marginale from Mexico will contribute to understanding the molecular landscape of this pathogen.
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页数:7
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