Conjugate vaccines and the carriage of Haemophilus influenzae type b

被引：88
|
作者：
Barbour, ML [1 ]
机构：
[1] JOHN RADCLIFFE HOSP, OXFORD OX3 9DU, ENGLAND
来源：
EMERGING INFECTIOUS DISEASES | 1996年 / 2卷 / 03期
关键词：
D O I：
10.3201/eid0203.960303
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Pharyngeal carriage of Haemophilus influenzae type b (Hib) is important in the transmission of Hib organisms, the pathogenesis of Hib disease, and the development of immunity to the bacterium. The remarkable success of current vaccination programs against Hib has been due in part to the effect of conjugate Hib vaccines in decreasing carriage of Hib. This review explores evidence for this effect, and discusses the possible mechanisms of the mucosal influence of Hib conjugate vaccines.
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页码：176 / 182
页数：7
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