Synthesis of 5-methylthioribose specifically bitritiated at the 5-C position

被引：0

作者：

Viegas, C ^{[1
]}

Zhang, Q ^{[1
]}

Guillerm, D ^{[1
]}

Guillerm, G ^{[1
]}

机构：

[1] Univ Reims, Chim Bioorgan Lab, UMR 6519 CNRS, UFR Sci, F-51687 Reims 2, France

来源：

JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS | 2001年 / 44卷 / 09期

关键词：

H-3; labelling; methylthioribose; methylthioribose kinase; enzymatic assay;

D O I：

10.1002/jlcr.498

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

An efficient and reliable method for the preparation of bitritiated-methylthioribose from a suitably protected 5-ketoazido-ribose derivative has been developed. This compound is an essential component in the assay of the microbial enzyme methylthioribose kinase, which is involved in the methionine salvage pathway from methylthioadenosine. Copyright (C), 2001 John Wiley & Sons, Ltd.

引用

页码：653 / 659

页数：7

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